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Rabbit Anti-NOL8/FITC Conjugated antibody (bs-6554R-FITC)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-6554R-FITC
英文名稱(chēng) Rabbit Anti-NOL8/FITC Conjugated antibody
中文名稱(chēng) FITC標(biāo)記的核仁蛋白8抗體
別    名 C9orf34; NOL8; NOL8_HUMAN; NOP132; Nucleolar protein 8; Nucleolar protein Nop132.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  腫瘤細(xì)胞生物標(biāo)志物  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 132kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NOL8 (841-885aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Summary: NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth

Function:
Plays an essential role in the survival of diffuse-type gastric cancer cells. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells.

Subunit:
Interacts with the GTP form of RRAGA, RRAGC and RRAGD. Interacts with NIP7. Interacts with DDX18; the interaction is RNA-dependent. Interacts with DDX47; the interaction is RNA-dependent.

Subcellular Location:
Nucleus, nucleolus. Note=Localizes in the nucleolar-organizing region during ribosome biogenesis.

Tissue Specificity:
Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle.

Post-translational modifications:
Phosphorylated

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

Database links:
UniProtKB/Swiss-Prot: Q76FK4.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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