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Rabbit Anti-IGFBP3/Biotin Conjugated antibody (bs-1434R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1434R-Bio
英文名稱 Rabbit Anti-IGFBP3/Biotin Conjugated antibody
中文名稱 生物素標記的胰島素樣生長因子結合蛋白3抗體
別    名 IGF BP3; IGF-BP3; Acid stable subunit of the 140 K IGF complex; Binding protein 29; Binding protein 53; BP 53; BP53; Growth hormone dependent binding protein; IBP 3; IBP3; IGF binding protein 3; IGFBP 3;IGFBP-3; Insulin Like Growth Factor Binding Protein 3; IBP3_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  生長因子和激素  轉錄調節因子  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, )
產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 30-35kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IGFBP3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
GFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by most tissues. Present in plasma.

Post-translational modifications:
Phosphorylation sites are present in the extracelllular medium.

Similarity:
Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain.

Database links:

Entrez Gene: 3486 Human

Entrez Gene: 16009 Mouse

Entrez Gene: 24484 Rat

Omim: 146732 Human

SwissProt: P17936 Human

SwissProt: P47878 Mouse

SwissProt: P15473 Rat

Unigene: 450230 Human

Unigene: 697535 Human

Unigene: 29254 Mouse

Unigene: 26369 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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