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Rabbit Anti-CD82/BF350 Conjugated antibody (bs-1470R-BF350)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1470R-BF350
英文名稱 Rabbit Anti-CD82/BF350 Conjugated antibody
中文名稱 BF350標記的腫瘤轉移抑制蛋白1抗體
別    名 4F9; Antigen detected by monoclonal and antibody IA4; C33; C33 antigen; CD 82; CD82 antigen; CD82 molecule; GR 15; GR15; IA 4; IA4; Inducible membrane protein; Inducible membrane protein R2; KAI 1; KAI1; Kangai 1; Kangai1; Metastasis suppressor Kangai 1; Metastasis suppressor Kangai1; R2 leukocyte antigen; CD82_HUMAN.   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  信號轉導  轉錄調節因子  細胞表面分子  細胞類型標志物  t-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD82
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.

Subunit:
Interacts directly with IGSF8.

Subcellular Location:
Membrane.

Tissue Specificity:
Lymphoid specific.

Similarity:
Belongs to the tetraspanin (TM4SF) family.

Database links:

Entrez Gene: 3732 Human

Entrez Gene: 12521 Mouse

Entrez Gene: 83628 Rat

Omim: 600623 Human

SwissProt: P27701 Human

SwissProt: P40237 Mouse

SwissProt: O70352 Rat

Unigene: 527778 Human

Unigene: 4261 Mouse

Unigene: 3022 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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