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Rabbit Anti-Pepsinogen C/BF647 Conjugated antibody (bs-1551R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1551R-BF647
英文名稱 Rabbit Anti-Pepsinogen C/BF647 Conjugated antibody
中文名稱 BF647標記的胃蛋白酶原C抗體
別    名 PG-C; PGC; Progastricsin; PEPC_HUMAN; Gastricsin; PEPC; pepsin C; preprogastricsin.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  信號轉導  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Chicken, Cow, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PG-C
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq].

Function:
Hydrolyzes a variety of proteins.

Subcellular Location:
Secreted.

Similarity:
Belongs to the peptidase A1 family.

Database links:

Entrez Gene: 5225 Human

Entrez Gene: 24864 Rat

Omim: 169740 Human

SwissProt: P20142 Human

SwissProt: P04073 Rat

Unigene: 1867 Human

Unigene: 9735 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

胃蛋白酶原C(PG-C)主要用于胃癌及其癌前病變易感性的關系。
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