97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲精品国产精品乱码,欧美一日本,av久久天堂三区
Rabbit Anti-CANX/RBITC Conjugated antibody (bs-1693R-RBITC)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1693R-RBITC
英文名稱 Rabbit Anti-CANX/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的鈣連蛋白抗體
別    名 Calnexin-ER membrane marker; CALNEXIN; CANX; Cell adhesion molecule with homology to l1cam precursor; CNX; D11Ertd153e; 1110069N15Rik; AI988026; FLJ26570; IP90; P90; Similar to calnexin; Major histocompatibility complex class I antigen-binding protein p88; CALX_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  染色質(zhì)和核信號(hào)  結(jié)合蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CANX
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]

Function:
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.

Subunit:
Interacts with MAPK3/ERK1. Interacts with KCNH2. Associates with ribosomes. Interacts with SGIP1; involved in negative regulation of endocytosis (By similarity). The palmitoylated form interacts with the ribosome-translocon complex component SSR1, promoting efficient folding of glycoproteins.

Subcellular Location:
Endoplasmic reticulum membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Post-translational modifications:
Phosphorylated at Ser-564 by MAPK3/ERK1. phosphorylation by MAPK3/ERK1 increases its association with ribosomes (By similarity). br>Palmitoylation by DHHC6 leads to the preferential localization to the perinuclear rough ER. It mediates the association of calnexin with the ribosome-translocon complex (RTC) which is required for efficient folding of glycosylated proteins.

Similarity:
Belongs to the calreticulin family.

Database links:

Entrez Gene: 821 Human

Entrez Gene: 12330 Mouse

Entrez Gene: 29144 Rat

Entrez Gene: 403908 Dog

Omim: 114217 Human

SwissProt: P24643 Dog

SwissProt: P27824 Human

SwissProt: P35564 Mouse

SwissProt: P35565 Rat

Unigene: 567968 Human

Unigene: 248827 Mouse

Unigene: 1762 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

內(nèi)質(zhì)網(wǎng)膜蛋白標(biāo)志物(ER membrane marker)
鈣連蛋白 calnexin 存在于內(nèi)質(zhì)網(wǎng)中,是內(nèi)質(zhì)網(wǎng)膜標(biāo)志物,屬于Ca2+的凝集素樣分子伴侶蛋白,可結(jié)合蛋白質(zhì)的寡糖鏈 ,防止蛋白質(zhì)彼此聚集和泛素化,避免折疊不完全的蛋白質(zhì)離開內(nèi)質(zhì)網(wǎng)。
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 国产免费国产 | 精品一区二区三区日本视频 | 国产一区福利在线 | 欧美性受xxxx黑人xyx | 伊人久久综合一区二区 | 国产精品久久久久无码人妻 | 精品无码一区二区三区在线 | 人妻aⅴ中文字幕 | 在线视屏 | 成人免费视频国一国二在线观看 | 国产香蕉一区二区三区 | 中出乱码av亚洲精品久久天堂 | 国内免费视频成人精品 | 国内精品一区二区 | 欧美成人高清 | 亚洲九色| 九九九九网站 | 欧美精品一国产成人综合久久 | 久草日B视频一二三区 | 国内精品国产三级国产 | 亚洲精品乱码久久久久膏 | 99热婷婷| 欢乐好声音1国语版免费观看 | 国产欧美色一区二区三区 | xvideos中文版网站入口 | 国产日韩欧美一区二区三区乱码 | 青青久久av | 麻豆av一区二区三区久久 | 国产欧美性 | 久久精品99久久久久久2456 | 人成在线免费网站 | 床震吃胸膜奶免费视频 | 成人av一级片 | 亚洲狠狠婷婷综合久久久久图片 | 国产精品三级 | 无码三级香港经典三级在线视频 | 欧美Ⅴ永久无码精品毛片 | 离异熟女不戴套456 免费操人 | 国产精品综合久久久精品综合蜜臀 | 日韩不卡高清视频 | 成人激情自拍 |