97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
97在线观看免费,向日葵色板视频,西西最大胆日本无码视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CANX/Cy5.5 Conjugated antibody (bs-1693R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1693R-Cy5.5
英文名稱 Rabbit Anti-CANX/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的鈣連蛋白抗體
別    名 Calnexin-ER membrane marker; CALNEXIN; CANX; Cell adhesion molecule with homology to l1cam precursor; CNX; D11Ertd153e; 1110069N15Rik; AI988026; FLJ26570; IP90; P90; Similar to calnexin; Major histocompatibility complex class I antigen-binding protein p88; CALX_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 免疫學  染色質和核信號  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, )
產品應用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CANX
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]

Function:
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.

Subunit:
Interacts with MAPK3/ERK1. Interacts with KCNH2. Associates with ribosomes. Interacts with SGIP1; involved in negative regulation of endocytosis (By similarity). The palmitoylated form interacts with the ribosome-translocon complex component SSR1, promoting efficient folding of glycoproteins.

Subcellular Location:
Endoplasmic reticulum membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Post-translational modifications:
Phosphorylated at Ser-564 by MAPK3/ERK1. phosphorylation by MAPK3/ERK1 increases its association with ribosomes (By similarity). br>Palmitoylation by DHHC6 leads to the preferential localization to the perinuclear rough ER. It mediates the association of calnexin with the ribosome-translocon complex (RTC) which is required for efficient folding of glycosylated proteins.

Similarity:
Belongs to the calreticulin family.

Database links:

Entrez Gene: 821 Human

Entrez Gene: 12330 Mouse

Entrez Gene: 29144 Rat

Entrez Gene: 403908 Dog

Omim: 114217 Human

SwissProt: P24643 Dog

SwissProt: P27824 Human

SwissProt: P35564 Mouse

SwissProt: P35565 Rat

Unigene: 567968 Human

Unigene: 248827 Mouse

Unigene: 1762 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

內質網膜蛋白標志物(ER membrane marker)
鈣連蛋白 calnexin 存在于內質網中,是內質網膜標志物,屬于Ca2+的凝集素樣分子伴侶蛋白,可結合蛋白質的寡糖鏈 ,防止蛋白質彼此聚集和泛素化,避免折疊不完全的蛋白質離開內質網。
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 少妇人妻陈艳和黑人教练 | 国产精品裸体一区二区三区 | 国产盗摄XXXX视频XXXⅩ | 精品国产综合乱码久久久久久 | 美女操av | 人人爽人人爽人人片A免费 国产国语农村妇女偷人视频 | aⅴ免费一区二区三区 | 波多野结衣成人在线观看 | 久久精品欧美精品日本韩国精品 | 国产亚洲日韩A欧美在线人成 | 国产成人AV一区二区三区无码 | 久久99精品无码一区二区三区 | 性刺激的大陆三级视频 | 国产草莓视频无码A在线观看 | 成人高清在线 | 国内精品久久久久精品 | AV中文无码乱人伦在线观看 | 国产精品久久久久久人妻精品 | 亚洲精品国产福利 | 熟妇性hqmaturetube | 亚洲成人999 | 午夜短视频 | Jαpαn丰满人妻HDXXXX | 91视频青娱乐 | 午夜影院免费视频 | 久综合网 | 少妇粉嫩小泬喷水视频WWW | 免费av毛片不卡无码 | 中国xxxx做受gay | 18无遮挡啪啪无码网站免费看 | 丰满妇女做A级毛片 | 亚洲一区在线日韩在线尤物 | 绿奴vk| 国产成人综合亚洲AV第一页 | 亚洲av无码乱码在线观看富二代 | 狠狠躁躁夜夜躁波多野结依 | 成人激情视频网站 | 国产又黄又爽胸又大免费视频 | 一本大道久久a久久精二百 国产av一级片日韩二区 | 亚洲精品综合精品自拍 | 在线高清理伦片a |