97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
天堂网av2014,91精品国产综合久久久久久久,久久久久久蜜av免费网站
Rabbit Anti-CANX/PE Conjugated antibody (bs-1693R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1693R-PE
英文名稱 Rabbit Anti-CANX/PE Conjugated antibody
中文名稱 PE標(biāo)記的鈣連蛋白抗體
別    名 Calnexin-ER membrane marker; CALNEXIN; CANX; Cell adhesion molecule with homology to l1cam precursor; CNX; D11Ertd153e; 1110069N15Rik; AI988026; FLJ26570; IP90; P90; Similar to calnexin; Major histocompatibility complex class I antigen-binding protein p88; CALX_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  染色質(zhì)和核信號  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CANX
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]

Function:
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.

Subunit:
Interacts with MAPK3/ERK1. Interacts with KCNH2. Associates with ribosomes. Interacts with SGIP1; involved in negative regulation of endocytosis (By similarity). The palmitoylated form interacts with the ribosome-translocon complex component SSR1, promoting efficient folding of glycoproteins.

Subcellular Location:
Endoplasmic reticulum membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Post-translational modifications:
Phosphorylated at Ser-564 by MAPK3/ERK1. phosphorylation by MAPK3/ERK1 increases its association with ribosomes (By similarity). br>Palmitoylation by DHHC6 leads to the preferential localization to the perinuclear rough ER. It mediates the association of calnexin with the ribosome-translocon complex (RTC) which is required for efficient folding of glycosylated proteins.

Similarity:
Belongs to the calreticulin family.

Database links:

Entrez Gene: 821 Human

Entrez Gene: 12330 Mouse

Entrez Gene: 29144 Rat

Entrez Gene: 403908 Dog

Omim: 114217 Human

SwissProt: P24643 Dog

SwissProt: P27824 Human

SwissProt: P35564 Mouse

SwissProt: P35565 Rat

Unigene: 567968 Human

Unigene: 248827 Mouse

Unigene: 1762 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

內(nèi)質(zhì)網(wǎng)膜蛋白標(biāo)志物(ER membrane marker)
鈣連蛋白 calnexin 存在于內(nèi)質(zhì)網(wǎng)中,是內(nèi)質(zhì)網(wǎng)膜標(biāo)志物,屬于Ca2+的凝集素樣分子伴侶蛋白,可結(jié)合蛋白質(zhì)的寡糖鏈 ,防止蛋白質(zhì)彼此聚集和泛素化,避免折疊不完全的蛋白質(zhì)離開內(nèi)質(zhì)網(wǎng)。
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 日韩新片在线观看 | 欧美亚洲小视频 | 国产视频91在线 | 成在人线AV无码免费高潮喷水 | 18久久白丝 | 国产伦精品免费视频 | 麻豆嫩芽忘忧草一区二区三区 | 亚洲欧美日韩网站 | 人善交VIDEOS欧美3D | 久久综合久久自在自线精品自 | 色综合久久久无码网中文 | 色哟哟~日韩精品 | 少妇愉情理伦片高潮日本 | 精品久久久久久无码人妻A片 | 亚洲精品在线观看视频 | 国产精品www | 国产v精品成人免费视频400条 | 97在线视频人妻无码 | 青青草国产成人a∨ | 国产亚洲精品资源在线26u91 | 狠狠狠的在啪线香蕉亚洲应用 | 人妻少妇精品无码专区 | 免费能直接在线观看黄的视频 | 久久精品国产亚洲aⅴ瑜伽 操处女逼小说 | 影音先锋中文字幕无码 | 欧美《熟妇的荡欲》在线观看 | 天天操天天干天天爽 | 国产精品无码无卡在线观看久 | 亚洲综合一区国产精品 | 国产精品久久久久久久久大全 | 精品国产青草久久久久96 | 人人爽人人爽人人片A免费 国产国语农村妇女偷人视频 | 久久久人精午夜精国 | 在线观看a视频 | 色亚洲天堂 | 91新视频在线观看 | 久久精品国产乱子伦 | 北条麻妃在线 | av蜜桃网| 久久久av免费 | 亚洲高清久久久 |