97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
av女优天堂在线观看,久久99精品久久久久久琪琪,中文无码日韩欧
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-CANX/PE-Cy3 Conjugated antibody (bs-1693R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1693R-PE-Cy3
英文名稱 Rabbit Anti-CANX/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的鈣連蛋白抗體
別    名 Calnexin-ER membrane marker; CALNEXIN; CANX; Cell adhesion molecule with homology to l1cam precursor; CNX; D11Ertd153e; 1110069N15Rik; AI988026; FLJ26570; IP90; P90; Similar to calnexin; Major histocompatibility complex class I antigen-binding protein p88; CALX_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  染色質(zhì)和核信號  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CANX
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]

Function:
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.

Subunit:
Interacts with MAPK3/ERK1. Interacts with KCNH2. Associates with ribosomes. Interacts with SGIP1; involved in negative regulation of endocytosis (By similarity). The palmitoylated form interacts with the ribosome-translocon complex component SSR1, promoting efficient folding of glycoproteins.

Subcellular Location:
Endoplasmic reticulum membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Post-translational modifications:
Phosphorylated at Ser-564 by MAPK3/ERK1. phosphorylation by MAPK3/ERK1 increases its association with ribosomes (By similarity). br>Palmitoylation by DHHC6 leads to the preferential localization to the perinuclear rough ER. It mediates the association of calnexin with the ribosome-translocon complex (RTC) which is required for efficient folding of glycosylated proteins.

Similarity:
Belongs to the calreticulin family.

Database links:

Entrez Gene: 821 Human

Entrez Gene: 12330 Mouse

Entrez Gene: 29144 Rat

Entrez Gene: 403908 Dog

Omim: 114217 Human

SwissProt: P24643 Dog

SwissProt: P27824 Human

SwissProt: P35564 Mouse

SwissProt: P35565 Rat

Unigene: 567968 Human

Unigene: 248827 Mouse

Unigene: 1762 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

內(nèi)質(zhì)網(wǎng)膜蛋白標志物(ER membrane marker)
鈣連蛋白 calnexin 存在于內(nèi)質(zhì)網(wǎng)中,是內(nèi)質(zhì)網(wǎng)膜標志物,屬于Ca2+的凝集素樣分子伴侶蛋白,可結(jié)合蛋白質(zhì)的寡糖鏈 ,防止蛋白質(zhì)彼此聚集和泛素化,避免折疊不完全的蛋白質(zhì)離開內(nèi)質(zhì)網(wǎng)。
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 无码精品每日更新精品久久久 | 国产精品久久久久无码人妻 | 秋霞鲁丝片无码一区二区 | 强行肉体进入hdxxxx办公室 | 国产又色又爽又黄又免费软件 | 亚洲综合另类小说色区 | 91亚洲一区精品 | 亚洲国产日韩在线人成蜜芽 | 超级碰碰人妻中文字幕 | 麻豆国产成人AV在线播放欲色 | 亚洲日本乱码一区二区三区 | 老司机精品视频在线 | 欧美黑人欧美精品刺激 | 亚洲日韩在线中文字幕第一页 | 久久精品亚洲成在人线av麻豆 | 久久国产精品二区 | 麻豆视频免费在线观看 | 7788成人网站免费观看 | AV无码精品1区2区3区 | 欧美成人一区二区三区在线观看 | 欧美成人看片一区二三区图文 | av在线免费播放不卡 | a级网站在线观看 | 精品男人天堂 | 在线中文免费视频 | 日欧在线 | 四虎影视在线影院在线观看 | 浴室洗澡偷拍一区二区 | 国产偷国产偷亚洲高清日韩 | 乱码视频午夜在线观看 | 毛片视频网站 | 欧美性xxxxx极品 | 国产古装三级在线 | 久久久99精品免费观看乱色 | 色国产精品一区在线观看 | 亚洲乱码日产精品bd在线观看 | porn久久| 免费黄网站在线观看 | 久久久久国产一区二区三区 | 波多老师无码av中字专区 | 99久久夜色精品国产亚洲av卜 |