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Rabbit Anti-SDF4/AP Conjugated antibody (bs-6732R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6732R-AP
英文名稱 Rabbit Anti-SDF4/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的基質細胞衍生因子4抗體(鈣結合蛋白)
別    名 CAB45; Calcium binding protein; PSEC0034; SDF 4; SDF-4; Stromal cell derived factor 4; CAB45_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  生長因子和激素  結合蛋白  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Horse, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SDF4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium dependent cellular activities. [provided by RefSeq, Sep 2011].

Function:
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment (By similarity).
Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini. [COFACTOR] Binds calcium (By similarity). Isoform 5 binds calcium.

Subunit:
Isoform 5 interacts with STXBP1; the interaction is enhanced in presence of calcium. Isoform 5 interacts with STX3.

Subcellular Location:
Isoform 1: Golgi apparatus lumen (By similarity).
Isoform 5: Cytoplasm. Cell projection, bleb. Note=Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs.

Tissue Specificity:
Ubiquitous. Isoform 5 is expressed in pancreas.

Similarity:
Belongs to the CREC family.
Contains 6 EF-hand domains.

Database links:
UniProtKB/Swiss-Prot: Q9BRK5.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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