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Rabbit Anti-MAGEA5/Cy3 Conjugated antibody (bs-6820R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6820R-Cy3
英文名稱 Rabbit Anti-MAGEA5/Cy3 Conjugated antibody
中文名稱 Cy3標記的黑色素瘤相關抗原5抗體
別    名 Cancer/testis antigen 1.5; Cancer/testis antigen family 1 member 5; CT1.5; MAGE 5 antigen; MAGE 5a antigen; MAGE 5b antigen; MAGE5; MAGEA4; Melanoma antigen family A 5; Melanoma associated antigen 5; MGC129526; MAGA5_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from hu MAGEA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
MAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene.

Function:
Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines.

Tissue Specificity:
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.

Similarity:
Contains 1 MAGE domain.

Database links:

Entrez Gene: 4104 Human

Entrez Gene: 100533997 Human

Omim: 300340 Human

SwissProt: P43359 Human

Unigene: 668021 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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