97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
99re6这里有精品热视频,久久国产精品一区,欧洲美女乱xxoo高潮大片
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-KCNA5/PE Conjugated antibody (bs-1837R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1837R-PE
英文名稱 Rabbit Anti-KCNA5/PE Conjugated antibody
中文名稱 PE標記的鉀電壓閥門通道混合器相關亞家族成員5抗體
別    名 Potassium voltage-gated channel subfamily A member 5; MGC117058; MGC117059; HCK1; HK2; HPCN1; Kv1; KV1.5; MGC25248; PCN1; Potassium channel 1; Potassium channel insulinoma and islet cell; ATFB7; PCN1; KCNA5_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12.

Function:
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. This channel displays rapid activation and slow inactivation. May play a role in regulating the secretion of insulin in normal pancreatic islets. Isoform 2 exhibits a voltage-dependent recovery from inactivation and an excessive cumulative inactivation.

Subunit:
Heterotetramer of potassium channel proteins. Interacts with DLG1, which enhances channel currents. Forms a ternary complex with DLG1 and CAV3 (By similarity). Interacts with UBE2I.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Pancreatic islets and insulinoma.

Post-translational modifications:
Sumoylated on Lys-221, and Lys-536, preferentially with SUMO3. Sumoylation regulates the voltage sensitivity of the channel.

DISEASE:
Familial atrial fibrillation 7 (ATFB7) [MIM:612240]: A familial form of atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.

Database links:

Entrez Gene: 3741 Human

Entrez Gene: 16493 Mouse

Entrez Gene: 25470 Rat

Omim: 176267 Human

SwissProt: P22460 Human

SwissProt: Q61762 Mouse

SwissProt: P19024 Rat

Unigene: 150208 Human

Unigene: 222831 Mouse

Unigene: 162789 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 日韩大片av | 国产内射合集颜射 | 日本视频一区二区 | 欧美视频精品在线观看 | 92国产精品午夜福利免费 | 女上男下gifxxoo吃奶 | 欧美激情视频一区二区 | 国产呦系列呦交 | 日本不卡一区二区三区 | 日本一区高清 | 无码三级香港经典三级在线视频 | av免费观看入口 | 国内在线一区 | 九色精品视频在线观看 | 99re在线视频精品 | 在线欧美成人 | 麻豆传媒观看 | 国产成人综合激情视频在线观看 | 无码H肉3D动漫在线观看 | 91av色 | 亚洲精品成人悠悠色影视 | 日韩av一区二区三区四区 | 成全免费高清观看在线电视 | 爽爽免费视频 | 中文字幕五区 | 国产片一区二区三区 | 在线看精品 | 日日噜噜噜夜夜爽爽狠狠片 | 国内精品久久久久影院优 | 狠狠色婷婷久久一区二区三区91 | 亚洲精品日本无v一区 | 99极品在线 | 女同久久精品国产99国产精品网站 | 亚洲视频精品 | 日韩亚洲区字幕 | 狠狠狠的在啪线香蕉亚洲应用 | 奇米777四色 | 精品欧美一区二区精品久久 | 久久精品成人免费观看三 | 夜色资源网站ye321 | 四川少妇BBB凸凸凸BBB |