97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
免费av一级,婷婷在线免费视频,中文字幕久久精品亚洲乱码
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-KCNA5/BF488 Conjugated antibody (bs-1837R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1837R-BF488
英文名稱 Rabbit Anti-KCNA5/BF488 Conjugated antibody
中文名稱 BF488標記的鉀電壓閥門通道混合器相關亞家族成員5抗體
別    名 Potassium voltage-gated channel subfamily A member 5; MGC117058; MGC117059; HCK1; HK2; HPCN1; Kv1; KV1.5; MGC25248; PCN1; Potassium channel 1; Potassium channel insulinoma and islet cell; ATFB7; PCN1; KCNA5_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12.

Function:
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. This channel displays rapid activation and slow inactivation. May play a role in regulating the secretion of insulin in normal pancreatic islets. Isoform 2 exhibits a voltage-dependent recovery from inactivation and an excessive cumulative inactivation.

Subunit:
Heterotetramer of potassium channel proteins. Interacts with DLG1, which enhances channel currents. Forms a ternary complex with DLG1 and CAV3 (By similarity). Interacts with UBE2I.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Pancreatic islets and insulinoma.

Post-translational modifications:
Sumoylated on Lys-221, and Lys-536, preferentially with SUMO3. Sumoylation regulates the voltage sensitivity of the channel.

DISEASE:
Familial atrial fibrillation 7 (ATFB7) [MIM:612240]: A familial form of atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.

Database links:

Entrez Gene: 3741 Human

Entrez Gene: 16493 Mouse

Entrez Gene: 25470 Rat

Omim: 176267 Human

SwissProt: P22460 Human

SwissProt: Q61762 Mouse

SwissProt: P19024 Rat

Unigene: 150208 Human

Unigene: 222831 Mouse

Unigene: 162789 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 十八禁羞羞视频爽爽爽 | 色欲久久久天天天综合影院 | 日本不卡免费在线观看 | 色呦呦久久久 | 日韩欧美在线综合 | 999www人成免费视频 | www.中出| 欧美亚洲日韩不卡在线在线观看 | 啊啊啊射了| 欧美一区二区三区蜜桃 | 台湾av一区二区三区 | 日韩精品一区二区三 | 色综合久久天天综合网 | 国产良妇出轨视频在线观看 | 午夜精品久久久久久久四虎 | 国产精品222 | 无码人妻精一区二区三区 | 国内免费视频成人精品 | 欧美国产日韩A在线视频Y | 亚洲精品久久无码 | 欧美重口另类在线播放二区 | 中文字幕亚洲码在线观看 | 黄色小说av | 妓女嫖客叫床粗话对白 | 激情三级 | 国产野精品久久久久久久不卡 | 色94色欧美setu | 学生在线精品一区二区 | 日韩第一页在线 | 日韩毛片免费视频一级特黄 | 两个人看的www免费 国产一区二区三区18 | 亚洲国产欧美在线人成最新 | 国产AV午夜精品一区二区入口 | 怡红院亚洲第一综合久久 | 成人综合婷婷国产精品久久蜜臀 | 18禁止进入1000部高潮网站 | 国产精品综合久久久精品综合蜜臀 | av片免费在线 | 99久久久无码国产精品古装 | 久久久久久久久久久美女 | 俄罗斯小younv另类 |