97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
成人高潮aa毛片免费视频,欧美成人在线播放视频,老子影院午夜伦不卡
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Ankyrin G/APC Conjugated antibody (bs-2415R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2415R-APC
英文名稱 Rabbit Anti-Ankyrin G/APC Conjugated antibody
中文名稱 APC標記的錨定蛋白G抗體
別    名 ANK-3; ANK-3; ANK3; ANK3_HUMAN; ankyrin 3 (G); Ankyrin 3, node of Ranvier (ankyrin G); Ankyrin 3, node of Ranvier; Ankyrin G119; Ankyrin-3; Ankyrin-G; brain specific ankyrin G; CHANK3.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  信號轉導  細胞粘附分子  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 481/220kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ankyrin G
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
human: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Alternatively spliced variants may be expressed in other tissues. Although multiple transcript variants encoding several different isoforms have been found for this gene, the full-length nature of only two have been characterized. [provided by RefSeq]
mouse: This gene encodes a member of the ankyrin protein family. Ankyrins link integral membrane proteins to the spectrin-based Ankyrins link integral membrane proteins to the spectrin-based cytoskeleton. Ankyrin family members share a protein structure which includes three independently folded domains: the N-terminal ankyrin repeat domain, the central spectrin-binding domain, and the C-terminal rod domain. This ankyrin functions as the major ankyrin in the kidney and may play a role in the polarized distribution of many integral membrane proteins to specific subcellular sites. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Function:
In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments.

Subunit:
Directly interacts with DMD and betaDAG1. This interaction does not interfere with binding between DMD and betaDAG1. It is also required for DMD and betaDAG1 retention at costameres (By similarity). Interacts (via N-terminal ANK repeats) with SCHIP1 isoform 5 (via C-terminus); this interaction is required for the localization at axon initial segments (AISs) and nodes of Ranvier (NRs) (By similarity). May be a constituent of a neurofascin/NRCAM/ankyrin G complex. Interacts with RHBG.

Subcellular Location:
Cytoplasm, cytoskeleton. Cell junction, synapse, postsynaptic cell membrane (By similarity). Lysosome (By similarity). Note=In skeletal muscle, localized at costameres and neuromuscular junctions (By similarity). In macrophages, associated with lysosomes (By similarity).

Tissue Specificity:
Expressed in brain, neurons and other tissues.

DISEASE:
Note=Genetic variations in ANK3 are associated with autism spectrum disorders susceptibility.

Similarity:
Contains 23 ANK repeats.
Contains 1 death domain.
Contains 2 ZU5 domains.

Database links:

Entrez Gene: 288 Human

Entrez Gene: 11735 Mouse

Entrez Gene: 361833 Rat

Omim: 600465 Human

SwissProt: Q12955 Human

SwissProt: G5E8K5 Mouse

SwissProt: Q4U206 Mouse

Unigene: 499725 Human

Unigene: 235960 Mouse

Unigene: 202383 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

錨定蛋白G是一個分子量在480KDa大分子細胞內蛋白。 錨蛋白(ankyrin)錨蛋白屬于聯結蛋白家族,廣泛存在于各種組織細胞中。錨蛋白連接整合膜蛋白到細胞骨架蛋白網絡,在多種細胞功能活動中起關鍵作用,參與機體生長、發育、細胞內蛋白轉運、細胞極性的建立和維持、細胞黏附、信號傳導以及mRNA轉錄等。
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 野花社区www官网在线观看 | 国产精品线在线精品 | 人妻系列无码专区无码专区 | 无码一区二区三区在线观看 | 中出一区二区三区 | 在线观看av每日更新免费 | 亚洲欧美色视频 | 日本啪啪网站永久免费 | 日日夜夜天天操 | 中文字幕人妻丝袜成熟乱 | 国产精品无码无卡无需播放器 | 中国白嫩精品bbwbbw | 日本看片一区二区三区高清 | 干干日日| 美女大胆作爱全过程 | 亚洲AV永久无码天堂网国产 | 亚洲欧洲日本无在线码天堂 | 國產精品倫一區二區三級視頻 | 一区二区三区精品视频免费看 | 一区二区三区日韩精品 | 蜜桃国内精品久久久久软件9 | 高潮一区二区 | 欧美xxxx色视频在线观看 | 欧美精品亚洲一区 | 日韩AV一中美AV一中文字慕 | 麻豆91精品 | a一级黄色| 男人女人做爽爽18禁免费 | 成人综合在线观看视频 | 国产下药迷晕一区二区三区在线看 | 天堂在线www资源在线 | 大地资源在线影视播放 | 亚洲精品一区二区三区在线 | 人人做人人看人人添 | 欧美色欧美亚洲高清在线观看 | 国产又粗又硬又猛的毛片视频 | 国产69精品久久久久777糖心 | 国产九九九精品视频 | 久久免费的精品国产v∧ | 国产日本一区二区 | 免费无码又爽又刺激动态图 |