97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
黄漫网站免费看,国产精品久久婷婷,人妻制服出轨中字在线
Rabbit Anti-KCNE1/HRP Conjugated antibody (bs-9928R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-9928R-HRP
英文名稱 Rabbit Anti-KCNE1/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標(biāo)記的鉀離子通道蛋白家族成員1抗體
別    名 Delayed rectifier potassium channel subunit IsK; Human cardiac delayed rectifier potassium channel protein; IKs producing slow voltage gated potassium channel subunit beta Mink; ISK; JLNS 2; JLNS; JLNS2; KCNE 1; LQT 5; LQT5; Minimal potassium channel; MinK; Potassium voltage gated channel Isk related family member 1; Potassium voltage gated channel Isk related subfamily member 1; Potassium voltage gated channel subfamily E member 1; KCNE1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 心血管  神經(jīng)生物學(xué)  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 15kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNE1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].

Function:
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).

Subunit:
Associates with KCNQ1/KVLQT1 and KCNH2/HERG.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed in heart, lung, kidney, testis, ovaries, small intestine, peripheral blood leukocytes. Not detected in pancreas, spleen, prostate and colon. Restrictively localized in the apical membrane portion of epithelial cells.

Post-translational modifications:
Phosphorylation inhibits the potassium current (By similarity).
N-glycosylation at Asn-26 occurs post-translationally, and requires prior cotranslational glycosylation at Asn-5.

DISEASE:
Defects in KCNE1 are the cause of Jervell and Lange-Nielsen syndrome type 2 (JLNS2) [MIM:612347]. JLNS2 is an autosomal recessive disorder characterized by congenital deafness, prolongation of the QT interval, syncopal attacks due to ventricular arrhythmias, and a high risk of sudden death.
Defects in KCNE1 are the cause of long QT syndrome type 5 (LQT5) [MIM:613695]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to exercise or emotional stress. KCNE1 mutants form channels that open slowly and close rapidly, thereby diminishing potassium currents.

Similarity:
Belongs to the potassium channel KCNE family.

Database links:

Entrez Gene: 3753 Human

Entrez Gene: 16509 Mouse

Entrez Gene: 397331 Pig

Entrez Gene: 25471 Rat

Omim: 176261 Human

SwissProt: P15382 Human

SwissProt: P23299 Mouse

SwissProt: Q9TUH9 Pig

SwissProt: P15383 Rat

Unigene: 121495 Human

Unigene: 299425 Mouse

Unigene: 9734 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 欧美aaaaaa午夜精品 | 国产一级淫片a按摩推澡按摩 | 澳门黄色网| 99久久精品免费看蜜桃的推荐词 | 成人特黄a级毛片免费视频 色一乱一伦一图一区二区精品 | 91.精品高清在线观看 | 国产无套中出学生姝 | free性欧美1819hd | 久久日韩国产精品免费 | 无码精品A∨在线观看中文 国产午夜精品片一区二区三区 | 中文字幕av一区二区三区 | 国产精品久久久久久久久久免费 | 婷婷久久国产对白刺激五月99 | 日韩精品在线一区二区 | 亚洲av无码久久寂寞少妇 | 国产在线一区不卡 | 国产日韩综合一区在线观看 | 啊啊啊射了 | 91av小视频| 伊人久久精品欧洲综合网 | 精品久久亚洲中文无码 | 日本r级未删减在线观看 | 国精产品一区二区三区四区 | 中文av一区 | 国产一区免费看 | 亚洲av无码乱码在线观看富二代 | 日韩欧美在线观看视频 | 欧美人与动牲交片免费播放 | 99国产精品国产免费观看 | bt天堂在线www中文 | 成人黄色片在线观看 | 亚洲在线网站 | 欧美群交射精内射颜射潮喷 | 另类综合日韩欧美亚洲 | 18禁无遮挡免费视频网站 | 国产精品无码一区二区三区无卡 | 中文字幕亚洲码在线观看 | 国产一级做a爰片久久 | 99在线视频免费 | www.久久成人 | 国产精品人妻久久久久 |