97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲制服卡通动漫,免费国产一区二区视频,一二三四国产精品
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-KCNE1/Biotin Conjugated antibody (bs-9928R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9928R-Bio
英文名稱 Rabbit Anti-KCNE1/Biotin Conjugated antibody
中文名稱 生物素標記的鉀離子通道蛋白家族成員1抗體
別    名 Delayed rectifier potassium channel subunit IsK; Human cardiac delayed rectifier potassium channel protein; IKs producing slow voltage gated potassium channel subunit beta Mink; ISK; JLNS 2; JLNS; JLNS2; KCNE 1; LQT 5; LQT5; Minimal potassium channel; MinK; Potassium voltage gated channel Isk related family member 1; Potassium voltage gated channel Isk related subfamily member 1; Potassium voltage gated channel subfamily E member 1; KCNE1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  神經生物學  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 15kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNE1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].

Function:
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).

Subunit:
Associates with KCNQ1/KVLQT1 and KCNH2/HERG.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed in heart, lung, kidney, testis, ovaries, small intestine, peripheral blood leukocytes. Not detected in pancreas, spleen, prostate and colon. Restrictively localized in the apical membrane portion of epithelial cells.

Post-translational modifications:
Phosphorylation inhibits the potassium current (By similarity).
N-glycosylation at Asn-26 occurs post-translationally, and requires prior cotranslational glycosylation at Asn-5.

DISEASE:
Defects in KCNE1 are the cause of Jervell and Lange-Nielsen syndrome type 2 (JLNS2) [MIM:612347]. JLNS2 is an autosomal recessive disorder characterized by congenital deafness, prolongation of the QT interval, syncopal attacks due to ventricular arrhythmias, and a high risk of sudden death.
Defects in KCNE1 are the cause of long QT syndrome type 5 (LQT5) [MIM:613695]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to exercise or emotional stress. KCNE1 mutants form channels that open slowly and close rapidly, thereby diminishing potassium currents.

Similarity:
Belongs to the potassium channel KCNE family.

Database links:

Entrez Gene: 3753 Human

Entrez Gene: 16509 Mouse

Entrez Gene: 397331 Pig

Entrez Gene: 25471 Rat

Omim: 176261 Human

SwissProt: P15382 Human

SwissProt: P23299 Mouse

SwissProt: Q9TUH9 Pig

SwissProt: P15383 Rat

Unigene: 121495 Human

Unigene: 299425 Mouse

Unigene: 9734 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲久本草在线中文字幕 | 欧美一区二区在线免费 | 亚洲华人play视频在线 | 这里只有精品在线观看 | 日韩一区二区三区四区区区 | 国产欧美久久一区二区三区 | 国产又色又爽又黄又免费软件 | www.一区二区三区.com | 日韩精品一区二区三区国语自制 | 亚洲久久成人 | 久久久天堂国产精品 | 亚洲精品久久久一区二区图片 | 久久99精品久久久噜噜最新章节 | 日韩高清在线观看 | 鲁一鲁啪一啪 | 精品人妻无码一区二区三区4 | 女人与牲口性恔配视频免费 | 成人激情av | 北条麻妃久久精品 | 亚洲一区二区在线免费视频 | 又大又粗欧美黑人AAAAA片 | 国产精品欧美综合亚洲 | 色欲狠狠躁天天躁无码中文字幕 | 2020亚洲一卡二卡三卡 | 国产精品扒开腿做爽爽爽视频 | 免费观看添你到高潮视频 | 国产精品96久久久久久又黄又硬 | 日韩一本之道一区中文字幕 | 天天爽狠狠噜天天噜日日噜 | 亚洲一片黄 | 欧美老人巨大xxxx做受视频 | 日韩精品久久久久久久软件91 | 99在线在线视频免费视频观看 | 国产精品久久久久77777 | 精品国产一卡2卡3卡4卡新区 | 中文无码亚洲精品字幕 | 色偷偷色噜噜狠狠网站久久 | 韩国午夜影院 | 亚洲第一天堂网 | 天天插夜夜骑 | 欧美狂野乱码一二三四区 |