97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
色在线国产,国产产在线精品亚洲AAVV,99热1
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-KCNE2/PE-Cy3 Conjugated antibody (bs-9930R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9930R-PE-Cy3
英文名稱 Rabbit Anti-KCNE2/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的鉀離子通道蛋白家族成員2抗體
別    名 ATFB4; cardiac voltage gated potassium channel accessory subunit 2; Kcne2; KCNE2_HUMAN; LQT5; LQT6; minimum potassium ion channel related peptide 1; Minimum potassium ion channel-related peptide 1 antibody minK related peptide 1; MinK-related peptide 1; MIRP1; Potassium channel subunit beta MiRP1; potassium channel subunit, MiRP1; potassium voltage gated channel subfamily E member 2; potassium voltage gated channel, Isk related family, member 2; Potassium voltage-gated channel subfamily E member 2; voltage-gated K+ channel subunit MIRP1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  神經生物學  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNE2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with KCNQ1/KVLTQ1 and elicit a voltage-independent current. May associate with HCN1 and HCN2 and increase potassium current.

Function:
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with KCNQ1/KVLTQ1 and elicit a voltage-independent current. May associate with HCN1 and HCN2 and increase potassium current.

Subunit:
Associates with KCNH2/ERG1. May associate with KCNQ1/KVLQT1, KCNQ2 and KCNQ3. Associates with HCN1 and probably HCN2 (By similarity).

Subcellular Location:
Membrane.

Tissue Specificity:
Highly expressed in brain, heart, skeletal muscle, pancreas, placenta, kidney, colon and thymus. A small but significant expression is found in liver, ovary, testis, prostate, small intestine and leukocytes. Very low expression, nearly undetectable, in lung and spleen.

DISEASE:
Defects in KCNE2 are the cause of long QT syndrome type 6 (LQT6) [MIM:613693]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to exercise or emotional stress. KCNE2 mutants form channels that open slowly and close rapidly, thereby diminishing potassium currents.
Defects in KCNE2 are the cause of familial atrial fibrillation type 4 (ATFB4) [MIM:611493]. Atrial fibrillation is a common disorder of cardiac rhythm that is hereditary in a small subgroup of patients. It is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure.

Similarity:
Belongs to the potassium channel KCNE family.

Database links:

Entrez Gene: 9992 Human

Entrez Gene: 246133 Mouse

Omim: 603796 Human

SwissProt: Q9Y6J6 Human

SwissProt: Q9D808 Mouse

Unigene: 551521 Human

Unigene: 679753 Human

Unigene: 156736 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Involvement in disease; Defects in KCNE2 are the cause of long QT syndrome type 6 (LQT6). Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to exercise or emotional stress. KCNE2 mutants form channels that open slowly and close rapidly, thereby diminishing potassium currents.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 大白肥妇BBVBBW高潮 | 国产在线精品无码不卡手机免费 | 免费人成再在线观看网站 | 日韩中文字幕无码高清毛片 | 欧美日韩国产成人高清视 | 久久久精品一区二区毛片免费看 | 亚洲超碰在线 | 亚洲一区中文日韩 | 扒开双腿吃奶呻吟做受 | 国产AV成人无码精品网站 | 国产精品久久久爽爽爽麻豆色哟哟 | 国产免费拔擦拔擦8x高清在线人 | 国产一卡2卡3卡4卡新区乱码在 | 99精品久久久久久久免费 | 波多野结衣成人在线观看 | 中文字幕亚洲综合久久菠萝蜜 | 就去色播| yp在线观看视频网址入口 | 大陆熟女丰满XXXXX富婆 | 亚洲三级黄色片 | 黄色一级久久 | 四虎新影院2019址 | 日本草逼 | 玩弄牲欲强老熟女 | 日韩不卡在线观看视频 | 欧美一区二区三区久久综合 | 青春草91| 欧美精品二区中文乱码字幕高清 | 高清性做爰大片免费视频 | 开心婷婷中文字幕 | 国产性色强伦免费看视频 | 国产精品自产拍在线观看55亚洲 | 国产区精品视频线二代 | 野花香影院在线观看视频免费 | 国产精品综合在线观看 | 狠狠色丁香婷婷综合久久来来去 | 激情综合色综合啪啪五月丁香搜索 | 欧美熟妇性XXXX欧美熟人多毛 | 亚洲一区精| xxx2高清在线观看免费视频 | 欧美人与动牲交欧美精品 |