97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
av的天堂,二人午夜免费观看在线视频,一性一交一伦一色一按—摩
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-NFAT5 (Ser1197)/Cy7 Conjugated antibody (bs-9474R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9474R-Cy7
英文名稱 Rabbit Anti-phospho-NFAT5 (Ser1197)/Cy7 Conjugated antibody
中文名稱 Cy7標記的磷酸化活化T細胞核因子5蛋白抗體
別    名 NFAT5 (phospho S1197); p-NFAT5(phospho S1197); Glutamine rich protein H65; KIAA0827; NF AT5; NF-AT5; NFAT 5; NFAT L1; NFAT like protein 1; NFAT5; NFAT5_HUMAN; NFATL 1; NFATL1; NFATZ; Nuclear factor of activated T cells 5; Nuclear factor of activated T cells 5 tonicity responsive; Nuclear factor of activated T cells; Nuclear factor of activated T-cells 5; OREBP; Osmotic response element binding protein; T cell transcription factor NFAT 5; T cell transcription factor NFAT5; T-cell transcription factor NFAT5; TonE binding protein; TonE-binding protein ; TonEBP; Tonicity responsive enhancer binding protein; Tonicity-responsive enhancer-binding protein.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 心血管  轉錄調節因子  淋巴細胞  t-淋巴細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 166kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human NFAT5 around the phosphorylation site of Ser1197
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Members of the NFAT (nuclear factor of activated T cells) family of transcription factors are related to NFkB/Rel proteins and form cooperative complexes with the AP-1 proteins, Fos and Jun, on DNA to regulate cytokine expression in T cells. NFAT proteins are widely expressed and alternatively modified to generate splice variants, and they are localized to both the cytosol (NFATc) and to the nucleus (NFATn). NFAT1, NFAT2, and NFAT4 are predominantly expressed in immune cells, and NFAT2 and NFAT3 are expressed at high levels in cardiac tissues. In addition to activating cytokine gene transcription, NFAT2 is also implicated in cardiac valve development, and NFAT3 is involved in cardiac hypertrophy. NFAT5 is detected in both immune and nonimmune cells and, like other NFAT proteins, contains a highly conserved Rel-like binding domain that mediates NFAT proteins associating with specific consensus sequences on DNA. NFAT proteins are activated by increases in intracellular calcium, which leads to the calmodulin-dependent phosphatase, calcineurin, dephosphorylating NFAT proteins. This activating event induces a conformational change in the protein structure that exposes the nuclear localization signal and facilitates the translocation of NFAT proteins from the cytosol into the nucleus.

Function:
Plays a role in the inducible expression of genes.Regulates hypertonicity-induced cellular accumulation of osmolytes.

Subunit:
Homodimer when bound to DNA, completely encircles its DNAtarget. Does not bind with Fos and Jun transcription factors.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. Also expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon.

Post-translational modifications:
Phosphorylated at Thr-135 by CDK5 in response to osmoticstress; this phosphorylation mediates its rapid nuclearlocalization.

Similarity:
Contains 1 RHD (Rel-like) domain.

Database links:

Entrez Gene: 10725 Human

Entrez Gene: 54446 Mouse

Entrez Gene: 307820 Rat

Omim: 604708 Human

SwissProt: O94916 Human

SwissProt: Q9WV30 Mouse

Unigene: 371987 Human

Unigene: 390057 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 中文字幕一区二区在线视频 | 国产免费观看一级国产 | 国产日产欧产精品 | 亚人在线播放国产中文字幕 | 怡红院福利视频 | 国产午夜亚洲精品 | 无码av一区在线观看免费 | 人妻三级日本三级日本三级极 | 乱人伦人妻中文字幕无码久久网 | 成人午夜做爰视频免费看 | 香港三级韩国三级日本三级 | 蜜臀久久99精品久久久久久网站 | 加勒比无码专区中文字幕 | 国产亚洲视频网站 | 中文字幕一区二区三区视频 | 中文字幕第十五页 | 毛片三区 | 亚洲国产日韩在线一区模特 | 色综合精品视频 | 欧美老熟妇乱子 | 任你搞在线观看 | 特黄色一级片 | 欧美aaaaaabbbbb | 午夜国产在线观看 | www.久久 | 开心五月激情综合婷婷 | 一区二区国产精品 | 精品乱码一区二区三四区视频 | 欧美噜噜久久久xxx 日韩av一区二区三区四区 | 色五月激情五月 | 野花社区WWW视频日本 | 91视频青娱乐| 在线看片无码永久免费AV | 国产成人a在线视频免费 | 直接观看黄网站免费视频 | 亚洲图片小说在线 | 成人免费A级毛片无码片2023 | 97免费超碰 | 精品福利在线观看 | 很黄的网站在线观看 | 欧美精品一区二区三区久久狼 |