97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产精品动漫一区二区三区,国产精品一区久久久久,免费黄网站日本
Rabbit Anti-AT2R2/Gold Conjugated antibody (bs-2133R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-2133R-Gold
英文名稱 Rabbit Anti-AT2R2/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的血管緊張素Ⅱ受體2抗體
別    名 AGTR 2; AGTR2; AGTR-2; AGTR2_HUMAN; angiotensin II receptor type 2; Angiotensin II Type 2; Angiotensin II type-2 receptor; Angiotensin receptor 2; AT 2; AT2; AT2R2 ATGR 2; ATGR2; ATGR-2; MRX 88; MRX88; Type 2 angiotensin II receptor; Type-2 angiotensin II receptor.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 心血管  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Horse, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human angiotensin II receptor type 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC?is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites.

Function:
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

Subunit:
Interacts with MTUS1.

Subcellular Location:
Cell membrane.

Tissue Specificity:
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine.

DISEASE:
Defects in AGTR2 are the cause of mental retardation X-linked type 88 (MRX88) [MIM:300852]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 186 Human

Entrez Gene: 11609 Mouse

Entrez Gene: 24182 Rat

Omim: 300034 Human

SwissProt: P50052 Human

SwissProt: P35374 Mouse

SwissProt: Q3US12 Mouse

SwissProt: P35351 Rat

Unigene: 405348 Human

Unigene: 2679 Mouse

Unigene: 162367 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 吃奶呻吟打开双腿做受视频 | 国产经典视频一区 | 一级片性生活 | 日本黄色五级片 | 久草在线色站 | 久久国产亚洲精品 | 深夜看国产毛片在线视频香蕉 | 欧美日p视频 | 日本视频黄 | a级毛片免费观看网站 | 插插插干干干 | 91视频免费在观看 | 国产极品在线观看 | 99热在线都是精品 | 成人软件在线观看 | 国产日韩欧美一区 | 日韩国产一级片 | 欧美最猛性| 久久综合99re88久久爱 | 涩涩亚洲乱码精品 | 无码av一区在线观看免费 | 色姑娘久 | 天堂а在线最新版在线 | 日韩人妻无码AV一区二区三区 | www.99日本精品片com | 日本一区二区三区在线视频 | 欧美成人69sss | 欧美黑人又粗又大久久久 | av成人在线观看 | 国产精品成人一区二区三区吃奶 | 国产麻豆一区二区三区在线观看 | 一本一本久久A久久综合精品蜜桃 | 成年网站在线观看 | 中文字幕一区二区在线视频 | 亚洲欧美日韩自偷自拍 | 经典老熟女ass | sese免费视频 | 日韩欧美人妻一区二区三区 | 久久99蜜桃综合影院免费观看 | 中文精品一区二区三区四区 | 日本伦理在线视频 |