97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
精品乱码一区二区三四区,亚洲成人av动漫,欧美成人一级大片
Rabbit Anti-AT2R2/BF594 Conjugated antibody (bs-2133R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-2133R-BF594
英文名稱 Rabbit Anti-AT2R2/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的血管緊張素Ⅱ受體2抗體
別    名 AGTR 2; AGTR2; AGTR-2; AGTR2_HUMAN; angiotensin II receptor type 2; Angiotensin II Type 2; Angiotensin II type-2 receptor; Angiotensin receptor 2; AT 2; AT2; AT2R2 ATGR 2; ATGR2; ATGR-2; MRX 88; MRX88; Type 2 angiotensin II receptor; Type-2 angiotensin II receptor.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 心血管  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human angiotensin II receptor type 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產(chǎn)品介紹 background:
Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC?is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites.

Function:
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

Subunit:
Interacts with MTUS1.

Subcellular Location:
Cell membrane.

Tissue Specificity:
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine.

DISEASE:
Defects in AGTR2 are the cause of mental retardation X-linked type 88 (MRX88) [MIM:300852]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 186 Human

Entrez Gene: 11609 Mouse

Entrez Gene: 24182 Rat

Omim: 300034 Human

SwissProt: P50052 Human

SwissProt: P35374 Mouse

SwissProt: Q3US12 Mouse

SwissProt: P35351 Rat

Unigene: 405348 Human

Unigene: 2679 Mouse

Unigene: 162367 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 91精品国产综合久久福利软件 | 亚洲国产精品va在线 | 国产播放啪视频免费视频 | 四虎国产成人 | 91污在线观看 | 久久久成人999亚洲区美女 | 最新精品国偷自产在线美女足 | 国产欧美亚洲精品第一区软件 | 伊人久久综合无码中文字幕 | 免费黄色一级 | 黄瓜视频入口永久免费观看 | 久久精品aⅴ无码中文字字幕 | 狼群社区视频WWW国语 | 日韩一级在线观看 | 日日摸夜夜添夜夜添无码免费视频 | 久久久久久久久久久高潮 | 久久精品国产亚洲aⅴ瑜伽 操处女逼小说 | 国产毛多水多女人a片 | 毛片a在线 | 亚洲日本va午夜中文字幕久久 | 蜜臀AV无码一区二区三区 | 岳好紧好湿夹太紧了好爽 | 国产精品无码免费视频二三区 | 91精品国产综合久久小仙女图片 | 国产午夜精品理论片a级探花 | 亚洲国产日韩av | 成人A片产无码免费奶头 | 九九热精品6 | 男女视频免费看 | 欧美亚洲欧美 | 免费观看日韩视频 | 少妇丰满大乳被男人揉捏视频 | 国产精品一区二区含羞草 | 成人国产一区二区三区精品麻豆 | 中文久久 | 欧美性猛交xxxx乱大交免费看 | 国内91视频| 国产精品高潮久久 | 黄色大全免费观看 | 国产超碰人人爽人人做AV | 亚洲欧美精 |