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Rabbit Anti-Ninjurin 1/BF488 Conjugated antibody (bs-11105R-BF488)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11105R-BF488
英文名稱 Rabbit Anti-Ninjurin 1/BF488 Conjugated antibody
中文名稱 BF488標記的神經(jīng)損傷誘導蛋白1抗體
別    名 Nerve injury induced protein 1; Nerve injury-induced protein 1; NIN1; NINJ1; NINJ1_HUMAN; NINJURIN; Ninjurin-1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經(jīng)生物學  細胞粘附分子  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ninjurin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Ninjurin family proteins are muli-pass membrane proteins induced by nerve injury in Schwann cells and dorsal root ganglion neurons. Nunjurin proteins act as homophilic cell adhesion molecules that promote axonal growth. Ninjurin proteins also play a role in the formation and function of other tissues. Ninjurin-1 is widely expressed in adult and embryonic tissues, particularly those with epithelial origin. Ninjurin-2 is also widely expressed, with highest levels in adult bone marrow and peripheral blood lymphocytes and embryo liver, thymus and heart. The genes that encode the Ninjurin proteins map to a region known to cause several genetic disorders, including hereditary sensory neuropathy type I and type II (HSN1 and HSN2). However, no link between mutations in the genes encoding Ninjurins and the diseases have been found.

Function:
Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin.

Similarity:
Belongs to the ninjurin family.

Database links:
UniProtKB/Swiss-Prot: Q92982.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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