97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
91素人在线,亚洲国产欧美在线看片xxoo,欧美亚洲综合久久
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Caspr2/PE-Cy3 Conjugated antibody (bs-11129R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11129R-PE-Cy3
英文名稱 Rabbit Anti-Caspr2/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的軸突相關(guān)CNTP2蛋白抗體(少突膠質(zhì)細胞)
別    名 Cell recognition molecule Caspr2; Cntnap2; CNTP2; CNTP2_HUMAN; Contactin-associated protein-like 2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 145kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Caspr2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
CASPR is a transmembrane glycoprotein of the neurexin superfamily that is highly enriched in regions of myelinated axons. The axons of myelinated nerves in the adult nervous system possess specialized subcellular structures essential for efficient and rapid action potential propagation. CASPR and the closely related molecule CASPR2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. While CASPR is present at the paranodal junctions, CASPR2 is precisely colocalized with Shaker-like K+ channels in the juxtaparanodal region. CASPR2 specifically associates with Kv1.1, Kv1.2, and their Kvbeta2 subunit. CASPR family members may play a role in the local differentiation of the axon into distinct functional subdomains.

Function:
May play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the juxtaparanodal region of the axo-glial junction.

Subunit:
Associates with KCNA2.

Subcellular Location:
Membrane.

Tissue Specificity:
Predominantly expressed in nervous system.

DISEASE:
Defects in CNTNAP2 are the cause of cortical dysplasia-focal epilepsy syndrome (CDFES) [MIM:610042]. Affected individuals manifest cortical dysplasia, focal epilepsy, relative macrocephaly, and diminished deep-tendon reflexes. Intractable focal seizures begin in early childhood, after which language regression, hyperactivity, impulsive and aggressive behavior, and mental retardation develop.
Genetic variations in CNTNAP2 influences susceptibility to autism type 15 (AUTS15) [MIM:612100]. Autism is a neurodevelopmental disorder characterized by disturbance in language, perception and socialization. The disorder is classically defined by a triad of limited or absent verbal communication, a lack of reciprocal social interaction or responsiveness, and restricted, stereotypical, and ritualized patterns of interests and behavior. Note=A chromosomal aberration involving CNTNAP2 is found in a patient with autism spectrum disorder. Paracentric inversion 46,XY,inv(7)(q11.22;q35). The inversion breakpoints disrupt the genes AUTS2 and CNTNAP2.

Similarity:
Belongs to the neurexin family.
Contains 2 EGF-like domains.
Contains 1 F5/8 type C domain.
Contains 1 fibrinogen C-terminal domain.
Contains 4 laminin G-like domains.

Database links:
UniProtKB/Swiss-Prot: Q9UHC6.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产精品男人影院在线播放 | 密桃av | 久久久激情网 | 亚洲精品无码国产 | 国产色噜噜噜91在线精品 | 亚洲欧洲日韩综合二区 | 色妞AV永久一区二区国产AV | 美女一区 | 女人被男人桶爽视频网站 | 日日添日日鲁日日夜 | 亚洲影院在线 | 被两个两个黑人吃奶4P | 一区二区视频免费在线观看 | 91国在线高清视频 | 日本JAPANESE丰满多毛 | 热99RE久久精品这里都是精品免费 | 亚洲中文字幕aⅴ无码天堂 成人黄网视频在线观看 | 四级黄色毛片 | 大香线蕉伊人久久爱 | 日韩处女网站 | 人人爽av| 91视频porny| 麻豆视频观看免费视频观看 | 在线观看亚洲欧美视频免费 | 国产精品资源一区二区三区 | 欧美日韩国产免费一区二区三区 | 亚洲久悠悠色悠在线播放 | 在线中文字幕国产 | 国产精品亚洲精品日韩已方 | 亚洲日韩国产AV无码无码精品 | 一区二三区四区乱 | 亚洲精品午夜视频 | 国产av无码一区二区二三区j | japanese国产打屁股网站 | 欧美13处交| 伊人精品视频在线观看 | 无码在线观看一区二区 | 蜜桃臀AV高潮无码 | 午夜精品二区 | 欧美美女久久 | 日本精品一区二区三区四区 |