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Rabbit Anti-PCDHGA12/Gold Conjugated antibody (bs-11152R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-11152R-Gold
英文名稱 Rabbit Anti-PCDHGA12/Gold Conjugated antibody
中文名稱 膠體金標記的原鈣粘蛋白γA12抗體
別    名 Cadherin 21; Cadherin21; Cadherin-21; CDH21; FIB3; Fibroblast cadherin FIB3; PCDH gamma A12; Protocadherin gamma subfamily A, 12; PCDGC_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 神經生物學  信號轉導  細胞粘附分子  細胞骨架  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHGA12
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protocadherein gamma cluster consists of three subfamilies (A, B and C). As a member of the gamma subfamily A, PCDHGA12 (Protocadherin gamma A12), also known as Cadherin-21 and Fibroblast cadherin-3, is a 932 amino acid protein that is one of 22 proteins encoded by the protocadherin gamma cluster. Typical of gamma protocadherins, PCDHGA12 contains six cadherin motifs and is a type I transmembrane receptor expressed in the central nervous system. Ubiquitously expressed with lowest levels in spleen, PCDHGA12 is thought to be involved in cell signaling. There are three isoforms of PCDHGA12 that are produced as a result of alternative splicing events.

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Contains 6 cadherin domains.

Database links:

Entrez Gene: 26025 Human

UniProtKB/Swiss-Prot: O60330.1



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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