97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
成年人在线视频观看,夜夜爽妓女8888视频免费 ,色www视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-SorLA/AP Conjugated antibody (bs-11166R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11166R-AP
英文名稱 Rabbit Anti-SorLA/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的低密度脂蛋白受體相關蛋白9抗體
別    名 C11orf32; FLJ21930; FLJ39258; gp250; LDLR relative with 11 ligand binding repeats; LDLR relative with 11 ligand-binding repeats; Low density lipoprotein receptor relative with 11 ligand binding repeats; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LR 11; LR11; LRP 9; LRP9; Mosaic protein LR11; SORL 1; SORL_HUMAN; SORL1; SorLA 1; SorLA; SorLA-1; Sortilin related receptor; Sortilin related receptor L(DLR class) A repeats containing; Sortilin-related receptor; Sorting protein related receptor containing LDLR class A repeats; Sorting protein-related receptor containing LDLR class A repeats;  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 235kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SorLA/LRP9
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Sortilin-related receptor, also known as Sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL (the main cholesterol-carrying lipoprotein of plasma) and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP, receptor-associated protein. SorLa is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous sorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. It is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.

Function:
Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction.

Subunit:
Belongs to the SORL1 family. Contains 5 BNR repeats. Contains 1 EGF-like domain. Contains 6 fibronectin type-III domains. Contains 11 LDL-receptor class A domains. Contains 5 LDL-receptor class B repeats.

Subcellular Location:
Membrane.

Tissue Specificity:
Expressed mainly in brain, where it is most abundant in the cerebellum, cerebral cortex and the occipital pole; low expression in the putamen and the thalamus. According to PubMed:9157966, found in spinal cord, testis, liver, kidney and pancreas with detectable levels in placenta, lung and heart. According to PubMed:8940146, expressed in the prostate, ovary, thyroid and spleen, but not found in kidney, liver, lung, skeletal muscle, bone marrow and adrenals.

Post-translational modifications:
The propeptide removed in the N-terminus may be cleaved by furin or homologous proteases.

Similarity:
Belongs to the VPS10-related sortilin family. SORL1 subfamily.
Contains 5 BNR repeats.
Contains 1 EGF-like domain.
Contains 6 fibronectin type-III domains.
Contains 11 LDL-receptor class A domains.
Contains 5 LDL-receptor class B repeats.

Database links:

Entrez Gene: 6653 Human

Entrez Gene: 20660 Mouse

Entrez Gene: 300652 Rat

Omim: 602005 Human

SwissProt: Q92673 Human

SwissProt: O88307 Mouse

SwissProt: Q9R0N2 Rat

Unigene: 368592 Human

Unigene: 121920 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 啪啪网址大全 | 国产精品熟女一区二区不卡 | 日本一道本免费 | 国产精久久久久久 | 999久久免费精品国产 | 亚洲精品综合精品自拍 | 亚洲日本一区二区三区在线 | 欧美一级淫片免费视频欧美辣图 | 天天爱综合网 | 在线观看中文视频 | 日韩天堂在线观看 | 午夜秒播 | 日本一级毛片免费播放 | 日本啪啪网站永久免费 | 久久久久久国产精品MV | 国内精品国产成人国产三级李采潭 | 扒开粉嫩小泬舌头伸进去视频 | 亚洲a一区二区三区 | 日本韩国欧美在线 | 亚洲视频久久久 | 国产性色强伦免费看视频 | 香蕉久久夜色精品国产更新时间 | 欧美成人看片一区二三区图文 | 国产午夜精品久久久久久免费视 | 五月丁香综合激情六月久久 | 亚洲一级视频在线观看 | 99re8这里有精品热视频8在线 | 国产黄色麻豆视频 | 成人午夜爽爽爽免费视频 | 久久婷婷五月综合色丁香 | 国产精品国产三级国产午 | 欧美一区二区三区在线看 | 色综合色天天久久婷婷基地 | 午夜羞羞影院免费播放在线观看 | 67194熟妇在线永久免费观看 | 蜜桃久久一区二区三区 | 久久精品亚洲成在人线av麻豆 | 麻豆国产成人AV在线播放欲色 | 欧美视频精品全部免费观看 | 欧洲视频一区 | 国产午夜精品免费一区二区三区视频 |