97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
黄网站在线免费看,亚洲成人福利,大地资源在线影视播放
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-RASSF5/HRP Conjugated antibody (bs-11168R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11168R-HRP
英文名稱 Rabbit Anti-RASSF5/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標記的RASSF5抗體
別    名 ras association domain-containing family protein 5; RASF5_HUMAN; New ras effector 1; Regulator for cell adhesion and polarization enriched in lymphoid tissues; RAPL; Nore1; Rapl.   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
產品應用 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASSF5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Function:
Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS1 and KRAS induced apoptosis.

Subunit:
Interacts directly with activated HRAS1; a RASSF5-STK4/MST1 complex probably associates with activated HRAS1. Interacts with KRAS. Probably interacts with Ras-like GTPases RRAS, RRAS2, MRAS, RAP1B, RAP2A and RALA. Can self-associate. Interacts with RSSF1 isoform A. The RSSF1 isoform A-RSSF5 heterodimer probably mediates the association of RSSF1 with HRAS1. Isoform 2 interacts with activated RAP1A andITGAL/LFA-1. Binds STK4/MST1, inhibiting STK4/MST1 autoactivation.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. unstimulated primary T-cells. Upon stimulation translocates to the leading edge and colocalizes with ITGAL/LFA-1 in the peripheral zone of the immunological synapse. Isoform 2 is localized to growing microtubules in vascular endothelial cells and is dissociated from microtubules by activated RAP1A.

Tissue Specificity:
Widely expressed. Frequently down-regulated in lung tumor cell lines and primary lung tumors.

Similarity:
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 Ras-associating domain.
Contains 1 SARAH domain.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 少妇小莹的yin荡生活下视频 | 国产免费国产 | 欧美人与动性xxxxx杂 | 久久精品无码观看TV | 亚洲精品综合精品自拍 | 日韩黄色a | 怡红院亚洲第一综合久久 | 囯产精品一品二区三区 | 色综合久久综合网 | 亚洲精品色婷婷在线影院 | 99国精产品一二三区 | 亚洲精品久久在线 | 亚洲精品视频久久久 | 中文无码一区二区视频在线播放 | 999久久a精品合区久久久 | 色视频一区二区 | 欧洲美女粗暴牲交视频免费 | 日韩第一页在线 | 中国亚州女人69内射少妇 | 美男被强行糟蹋np各种play | 在线天堂一区 | 91freehdxxxx欧美 | 日韩精品区一区二区三vr | 99久久国产免费大片 | 久久亚洲sm情趣捆绑调教 | 在线观看你懂的网址 | 免费不卡 | 国产精品12区| 男女性高爱潮免费网站 | 亚洲人成精品久久久久 | 91丨九色丨丰满人妖 | www.se天堂| 2022国产在线 | 国产亚洲精品欧洲在线观看 | 一区二区三区国产免费 | 国产99视频精品免费播放照片 | 国产激情无码视频在线播放性色 | 欧美GAY猛男GAYA片18禁 | 色欲av久久无码影院色戒 | 在线观看va | 日韩欧美在 |