97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
大吊一区二区,国产a视频免费观看,英国少妇色xxxxx
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-RASSF5/BF594 Conjugated antibody (bs-11168R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11168R-BF594
英文名稱 Rabbit Anti-RASSF5/BF594 Conjugated antibody
中文名稱 BF594標記的RASSF5抗體
別    名 ras association domain-containing family protein 5; RASF5_HUMAN; New ras effector 1; Regulator for cell adhesion and polarization enriched in lymphoid tissues; RAPL; Nore1; Rapl.   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASSF5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Function:
Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS1 and KRAS induced apoptosis.

Subunit:
Interacts directly with activated HRAS1; a RASSF5-STK4/MST1 complex probably associates with activated HRAS1. Interacts with KRAS. Probably interacts with Ras-like GTPases RRAS, RRAS2, MRAS, RAP1B, RAP2A and RALA. Can self-associate. Interacts with RSSF1 isoform A. The RSSF1 isoform A-RSSF5 heterodimer probably mediates the association of RSSF1 with HRAS1. Isoform 2 interacts with activated RAP1A andITGAL/LFA-1. Binds STK4/MST1, inhibiting STK4/MST1 autoactivation.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. unstimulated primary T-cells. Upon stimulation translocates to the leading edge and colocalizes with ITGAL/LFA-1 in the peripheral zone of the immunological synapse. Isoform 2 is localized to growing microtubules in vascular endothelial cells and is dissociated from microtubules by activated RAP1A.

Tissue Specificity:
Widely expressed. Frequently down-regulated in lung tumor cell lines and primary lung tumors.

Similarity:
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 Ras-associating domain.
Contains 1 SARAH domain.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久香蕉精品 | www.四虎精品 | 亚洲黄色在线免费观看 | 成人精品视频网站 | 国产V精品V欧美V日韩V | 国产又粗又大又黄AA片爱豆 | 妖精视频一区 | 91精品无毒不卡 | 夜色资源www.999 | 欧美日韩激情在线 | 97精品在线观看 | 亚洲毛片AV日韩AV无码 | 亚洲乱码中文字幕小综合 | 日韩视频一区在线观看 | 亚洲精品一区二区成人 | 久久久久久国产精品免费无遮挡 | 一二三四中文在线 | 天天舔天天干天天操 | 国产免费人成视频网站在线18 | 亚洲欧美国产日韩精品 | 亚洲色欲色欱WWW在线 | 欧美《熟妇的荡欲》在线观看 | 00粉嫩高中生洗澡偷拍视频 | 91九色性视频 | 国产裸体舞一区二区三区 | 日本在线视频播放 | 国产精品视频麻豆 | 9l国产精品久久久久麻豆 | 国产精品久久久亚洲女人 | 老司机福利在线视频 | 久久99亚洲精品久久 | 亚洲精品一区二区三区中文字幕 | www.日本不卡 | 麻豆视频在线免费看 | 久草片免费福利资源 | 中国丰满大乳乳液 | 在线观看91精品国产入口 | 欧洲成人免费 | 久久久久久草 | 我要看免费毛片 | 亚洲男人的天堂在线 |