97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
A片免费网址在线观看,日韩欧美国产区,禁漫免费观看
Rabbit Anti-CACNA1F/BF350 Conjugated antibody (bs-11245R-BF350)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11245R-BF350
英文名稱(chēng) Rabbit Anti-CACNA1F/BF350 Conjugated antibody
中文名稱(chēng) BF350標(biāo)記的鈣離子通道a1F亞型抗體
別    名 CACNA 1F; CACNAF; CACNAF1; Calcium channel voltage dependent alpha 1F subunit; Calcium channel voltage dependent L type alpha 1F subunit; Cav1.4; Cav1.4alpha1; COD 3; COD3; CORDX 3; CORDX; CORDX3; CSNB2A; CSNBX 2; CSNBX2; JM 8; JM8; JMC 8; JMC8; Voltage ated calcium channel subunit alpha Cav1.4; Voltage ependent L ype calcium channel subunit alpha F; CAC1F_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  通道蛋白  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 221kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CACNA1F
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Voltage-dependent Ca2+ channels mediate Ca2+ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca2+-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression.Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. L-type Ca2+ currents initiate muscle contraction, endocrine secretion, and gene transcription, and can be regulated through second-messenger activated protein phosphorylation pathways. L-type calcium channels may form macromolecular signaling complexes with G protein-coupled receptors, thereby enhancing the selectivity of regulating specific targets.

Function:
CACNA1F (Calcium channel, voltage-dependent, L type, alpha 1F subunit) is a subunit of a voltage-dependent calcium channel complex. Voltage-gated calcium channels mediate the entry of calcium ions into excitable cells. CACNA1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the "high-voltage activated" (HVA) group and are blocked by dihydropyridines (DHP).

Subunit:
Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity. Interacts (via IQ domain) with CABP4; in a calcium independent manner (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expression in skeletal muscle and retina.

DISEASE:
Defects in CACNA1F are the cause of congenital stationary night blindness type 2A (CSNB2A) [MIM:300071]. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision.
Defects in CACNA1F are the cause of cone-rod dystrophy X-linked type 3 (CORDX3) [MIM:300476]. CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa.
Defects in CACNA1F are the cause of Aaland island eye disease (AIED) [MIM:300600]; also known as Forsius-Eriksson type ocular albinism. On the Aaland island in the Baltic Sea, AIED is an X-linked recessive retinal disease characterized by a combination of fundus hypopigmentation, decreased visual acuity due to foveal hypoplasia, nystagmus, astigmatism, protan color vision defect, myopia, and defective dark adaptation. Except for progression of axial myopia, the disease can be considered to be a stationary condition. Electroretinography reveals abnormalities in both photopic and scotopic functions.

Similarity:
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1F subfamily.

Database links:

Entrez Gene: 778 Human

Omim: 300110 Human

SwissProt: O60840 Human

Unigene: 632799 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 狠狠躁夜夜a产精品视频 | 午夜私人视频 | 啦啦啦资源视频在线完整免费高清 | 亚洲一区二区制服在线 | 国产第二区国产一级片播放 | 久久国产精品小视频 | 亚洲aⅴ久久精品 | 日韩欧美在线播放 | 成网在线看 | 麻豆影院 | 亚洲高清视频在线 | 中文字幕乱码中文乱码51精品 | 全黄h全肉短篇禁乱np慕浅浅 | 欧美亚洲日本 | 深夜看国产毛片在线视频香蕉 | 欧美色图bt| 亚洲av日韩av无码专区 | 488成人啪啪片 | 一区二区三区四区五区中文字幕 | 国产日韩一级片 | 正在播放国产对白孕妇作爱 | 欧美暴力analvideos| 啪一啪日一日 | 正在做饭的少妇中文字幕 | 好爽好大久久久级淫片毛片小说 | 久久精品国产第一区二区三区 | 国产呻吟久久久久久久92 | 在线黄色观看 | 免费无码又爽又刺激动态图 | 午夜在线免费观看视频 | 国产香蕉一区二区三区 | 久久这里精品国产99丫e6 | 免费aa大片| 日产特黄级日产片 | 欧美极品一区 | 香蕉国产9 | 性色av蜜臀av牛牛影院 | 国产高清一区二区三区视频 | 久久99蜜桃综合影院免费观看 | 爽妇网国产精品 | 日韩三级免费 |