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Rabbit Anti-PTP zeta/PE-Cy5.5 Conjugated antibody (bs-11327R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11327R-PE-Cy5.5
英文名稱 Rabbit Anti-PTP zeta/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的磷酸蛋白聚糖PTPRZ抗體
別    名 Phosphacan; 3F8 chondroitin sulfate proteoglycan; 3H1 keratan sulfate proteoglycan; HPTPZ; HPTPzeta; Phosphacan; Protein tyrosine phosphatase receptor type Z polypeptide 2; Protein tyrosine phosphatase, receptor type, Z polypeptide 1; Protein tyrosine phosphatase, receptor type, zeta polypeptide 1; PTP-ZETA; PTP18; PTPRZ; PTPRZ1; PTPZ; R PTP zeta 2; R-PTP-zeta; Receptor type tyrosine phosphatase beta/zeta; Receptor-type tyrosine-protein phosphatase zeta; RPTP-BETA; RPTPB; RPTPbeta; PTPRZ_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  激酶和磷酸酶  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 251kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Phosphacan
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
PTP zeta (receptor-type protein tyrosine phosphatase zeta) is a type I membrane protein chondroitin sulfate proteoglycan with a transmembrane domain and intracellular tyrosine phosphatase domains. PTP zeta may be involved in the regulation of specific developmental processes in the CNS. PTP zeta is developmentally regulated in the brain and specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. PTP zeta belongs to the protein-tyrosine phosphatase family and contains 1 eukaryotic-type carbonic anhydrase domain, 1 fibronectin type III domain and 2 tyrosine-protein phosphatase domains.

Function:
May be involved in the regulation of specific developmental processes in the CNS.

Subunit:
The carbonic-anhydrase like domain binds to contactin (By similarity).

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
Contains 1 alpha-carbonic anhydrase domain.
Contains 1 fibronectin type-III domain.
Contains 2 tyrosine-protein phosphatase domains.

Database links:

Entrez Gene: 5803 Human

Entrez Gene: 19283 Mouse

Entrez Gene: 25613 Rat

Omim: 176891 Human

SwissProt: P23471 Human

SwissProt: Q62656 Rat

Unigene: 489824 Human

Unigene: 10088 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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