97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
黄色国产免费观看,亚洲欧美在线综合图区,2024最新毛片
Rabbit Anti-ABCA4/BF555 Conjugated antibody (bs-11356R-BF555)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-11356R-BF555
英文名稱(chēng) Rabbit Anti-ABCA4/BF555 Conjugated antibody
中文名稱(chēng) BF555標(biāo)記的神經(jīng)元突觸膜胞外分泌調(diào)節(jié)蛋白1抗體
別    名 RIM1; ABCA4; CORD7; Rab-3-interacting molecule 1; Rab-3-interacting protein 2; RAB3 interacting protein 2; Rab3-interacting molecule 1; Rab3ip1; RAB3IP2; Regulating synaptic membrane exocytosis 1; Regulating synaptic membrane exocytosis protein 1; RIM 1; RIM; Rims1 (gene name); RIMS1; RIMS1_HUMAN; Serg1 (gene name); KIAA0340; MGC167823; MGC176677; Nbla00761.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞類(lèi)型標(biāo)志物  細(xì)胞膜蛋白  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 189kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RIM1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012].

Function:
Rab effector involved in exocytosis. May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity.

Subunit:
Binds RAB3A, RAB3B and RAB3D that have been activated by GTP-binding. Interacts with RAB3C, RAB10, RAB26 AND RAB37. Binds UNC13A. Interacts with BZRAP1/RIMBP1 and RIMBP2. Interacts with PPFIA3 and PPFIA4. Interacts with ERC1 (By similarity). Binds SNAP25, SYT1 and CACNA1B. Interaction with SYT1 is enhanced by calcium ions. Interaction with SNAP25 is weaker in the presence of calcium ions.

Subcellular Location:
Cell membrane; Peripheral membrane protein (By similarity). Cell junction, synapse (By similarity). Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein (By similarity).

Tissue Specificity:
Detected in brain and retina.

Post-translational modifications:
Phosphorylated by BRSK1 (By similarity).

DISEASE:
Defects in RIMS1 may be a cause of cone-rod dystrophy type 7 (CORD7) [MIM:603649]. CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa.

Similarity:
Contains 2 C2 domains.
Contains 1 FYVE-type zinc finger.
Contains 1 PDZ (DHR) domain.
Contains 1 RabBD (Rab-binding) domain.

Database links:

Entrez Gene: 281584 Cow

Entrez Gene: 24 Human

Entrez Gene: 11304 Mouse

Entrez Gene: 497268 Xenopus laevis

Omim: 601691 Human

SwissProt: O02698 Cow

SwissProt: P78363 Human

SwissProt: O35600 Mouse

SwissProt: Q5F1L3 Xenopus laevis

Unigene: 416707 Human

Unigene: 3918 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 免费观看一级特黄欧美大片 | 免费黄色网址在线观看 | 噜噜在线视频 | 久久高清中文字幕 | 暴力调教一区二区三区 | 国产精品国产三级国AV | 国产精品一区二区av日韩在线 | 色综合精品久久久久久久 | 人妻系列无码专区久久五月天 | 国内自产拍自拍A免费毛片 无码人妻精品一区二区三区久久 | 僵尸启示录没删掉版免费观看 | 亚洲精品无码精品MV在线观看 | 亚洲另类第一页 | 国产成人精品综合久久久久99 | 18禁裸乳无遮挡自慰免费动漫 | 久久美利坚合众国AV无码 | 人人人草 | 国产精品成人亚洲一区二区 | 91精品在线影院 | 影音先锋亚洲熟女av网 | 永久黄软件免费观看 | 欧美激情网站在线观看 | 久久人人爽人人爽人人片DVD | 国产精品高清视亚洲乱码 | 国产av一级毛片 | 99午夜| 国内精品国产三级国产 | 久久婷婷五月综合色丁香 | 澳门一级毛片 | 亚洲精品99999 | 久久一二区 | 在线观看国产一区二区三区 | 麻豆精品在线视频 | 欧美黑人肉体狂欢大派对 | 毛片视频软件 | 中文字幕第一区二区 | 人av在线| 成人在线观看亚洲 | 国产精品久久久久久久毛片动漫 | 一色一伦一区二区三区 | 亚洲一区成人 |