97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
福利网站在线播放,国语对白做受xxxxx在线,亚洲国产欧美在线人成最新
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Oligophrenin 1/BF488 Conjugated antibody (bs-11469R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11469R-BF488
英文名稱 Rabbit Anti-Oligophrenin 1/BF488 Conjugated antibody
中文名稱 BF488標記的精神發育遲滯相關蛋白Oligophrenin-1抗體
別    名 Oligophrenin1; Oligophrenin-1; OPHN1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, Dog, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 92kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from huamn Oligophrenin 1 (418-465aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Ras p21 can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (1,2). Interaction of Ras p21 with GTPase activating protein (GAP) can increase the rate of hydrolysis of Ras p21-bound GTP by as much as 1000-fold (3). In mitogenically activated and tyrosine kinase-transformed cells, Ras GAP forms a complex with a protein designated p190 (4). At its amino terminus, p190 contains sequence motifs characteristic of all known GTPases, whereas the carboxy terminus contains sequences similar to those found in the Bcr gene product, n-chimerin and Rho GAP, all of which exhibit intrinsic GAP activity (4,5). Oligophrenein-1 is an additional protein with GTPase activating activity. Oligophrenein-1 is a RhoGAP protein that stimulates GTP hydrolysis of Rho subfamily members and is involved in cell migration, morphogenesis and axon outgrowth (6).

Function:
Stimulates GTP hydrolysis of members of the Rho family. Could activates GTPase targets that are known to affect cell migration and outgrowth of axons and dendrites.

Subunit:
Interacts with HOMER1. Interacts with AMPA receptor complexes. Interacts with SH3GL2 (endophilin-A1)

Subcellular Location:
Cell junction, synapse. Cell projection, axon. Cell projection, dendritic spine. Note=Present in both presynaptic and postsynaptic sites

Tissue Specificity:
Expressed in brain.

DISEASE:
Defects in OPHN1 are the cause of mental retardation X-linked OPHN1-related (MRXSO) [MIM:300486]; formerly designated MRX60. MRXSO is a syndromic mental retardation. Patients present mental retardation associated with cerebellar hypoplasia and distinctive facial dysmorphism.

Similarity:
Contains 1 PH domain.
Contains 1 Rho-GAP domain.

Database links:

Entrez Gene: 4983 Human

Omim: 300127 Human

SwissProt: O60890 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 狼人青草久久网伊人 | 中文av之家 | 人妻仑乱a级毛片免费看 | 日日添日日鲁日日夜 | 欧美性猛交xxxx乱大交免费看 | 亚洲第一区久久 | 国产成人欧美一区二区三区一色天 | 99re热精品 | 91大神视频在线免费观看 | 欧美在线观看视频 | 九九热在线视频观看这里只有精品 | 日韩爱爱片| 久久免费在线 | 久久九九热 | 精品国产人妻一区二区三区 | 精品国产乱码一区二区三区 | 国内黄色大片 | 亚洲草草| 裸体午夜一级视频 | 中国a一片一级一片 | 一级二级三级毛片 | 丰满妇女做a级毛片免费观看 | 精品国产乱码久久久久久浪潮 | 亚洲视频成人在线 | 少妇穿牛仔裤一级av毛片 | 欧美日韩激情一区二区 | 国产亚洲日韩A欧美在线人成 | 国产视频在线看 | 我真的不是气运之子动漫免费观看 | 色久悠悠在线观看 | 日本高清视频WWW夜色资源 | 99国产欧美 | 亚洲精品无码久久久久AV老牛 | 免费在线视频一区 | 日韩综合av | 观看av| 中文字幕无码乱码人妻系列蜜桃 | 日韩欧美精品在线视频 | 人妻系列无码专区久久五月天 | 亚洲av无码免费成人av | 最近中文字幕免费MV在线视频 |