| 產(chǎn)品編號 | bs-11522R-BF488 |
| 英文名稱 | Rabbit Anti-NPY4R/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的神經(jīng)肽Y受體4抗體 |
| 別 名 | Neuropeptide Y receptor type 4; Neuropeptide Y receptor Y4; NPY 4R; NPY R4; NPY Y4; NPY Y4 receptor; NPY-Y4 receptor; NPY4 R; NPY4-R; NPY4R; NPY4R_HUMAN; NPYR 4; NPYR4; NPYY 4; NPYY4; NPYY4-R; Y4 receptor. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NPY4R 151-250aa |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY5-R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY1-R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY5-R maps to human chromosome 4q32.2. NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31. Function: NPY4R has been reported to be expressed in bladder, brain, colon, endometrium, heart, lung, nasal mucosa, penis, prostate, skeletal muscle, small intestine, stomach, and vessel. ESTs have been isolated from human colon and head/neck libraries. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 101141797 Gorilla Entrez Gene: 100052105 Horse Entrez Gene: 100996758 Human Entrez Gene: 5540 Human Omim: 601790 Human SwissProt: P50391 Human Unigene: 524719 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
