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Rabbit Anti-ZDHHC-12/PE-Cy7 Conjugated antibody (bs-6958R-PE-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-6958R-PE-Cy7
英文名稱 Rabbit Anti-ZDHHC-12/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的鋅指蛋白Zdhhc12抗體
別    名 DHHC12; DHHC-12; Palmitoyltransferase ZDHHC12; ZDH12_HUMAN; Zdhhc12; Zinc finger DHHC domain-containing protein 12; DHHC-12; Probable palmitoyltransferase ZDHHC12; ZDH12_HUMAN; ZDHHC12; Zinc finger DHHC domain-containing protein 12; Zinc finger DHHC type containing 12; Zinc finger protein 400; ZNF400.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 30kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZDHHC-12
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC12 (zinc finger, DHHC domain containing 12), also known as ZNF400, is a 267 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to a S-palmitoyl protein and free CoA. Three isoforms exist due to alternative splicing events. The gene encoding ZDHHC12 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Chromosome 9 is considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype.

Subcellular Location:
Membrane; Multi-pass membrane protein

Similarity:
Belongs to the DHHC palmitoyltransferase family.
Contains 1 DHHC-type zinc finger.

Database links:

Entrez Gene: 505354 Cow

Entrez Gene: 608478 Dog

Entrez Gene: 100066906 Horse

Entrez Gene: 84885 Human

Entrez Gene: 100519816 Pig

Entrez Gene: 366014 Rat

SwissProt: Q96GR4 Human

SwissProt: Q6DGF5 Rat

Unigene: 133122 Human

Unigene: 95138 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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