97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
天天射天天干,伦伦影院欧美伦理,天天射美女
Rabbit Anti-SRGAP1/BF594 Conjugated antibody (bs-11601R-BF594)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-11601R-BF594
英文名稱(chēng) Rabbit Anti-SRGAP1/BF594 Conjugated antibody
中文名稱(chēng) BF594標(biāo)記的Rho GTP酶激活蛋白13抗體
別    名 ARHGAP13; FLJ22166; KIAA1304; RGD1566260; Rho GTPase activating protein 13; SLIT ROBO Rho GTPase activating protein 1; SRGAP 1; SRGP1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SRGAP1 (51-150aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
SRGAPs contain a highly conserved overall primary structure and play an important role in the cell facilitating Slit-robo signaling in cell migration and axon guidance. SRGAP1 (Slit-robo Rho GTPase activating protein 1), also known as ARHGAP13 (Rho GTPase activating protein 13), functions as a GTPase-activating protein for Cdc42 and Rho A. Expressed in kidney, testis, lung and brain, SRGAP1 contains an FCH (Fes/CIP4 homology) domain, a Rho-GAP domain and an SH3 domain. In the presence of Slit, SRGAP1 (via its SH3 domain) binds to the CC3 motif in robo (a protein responsible for mediating the repulsive effect of Slit) with higher affinity and inhibits Cdc42 activity in a robo/SRGAP-dependent manner. More specifically, SRGAP1 increases the intrinsic GTPase activity of Cdc42, thereby converting it to its inactive, GDP-bound form. Inactivation of Cdc42 ultimately leads to a decrease in actin polymerization.

Function:
GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.

Subunit:
Homodimer (Probable). Forms heterooligomer with SRGAP2 and SRGAP3 through its F-BAR domain. Interacts with ROBO1, CDC42 and RHOA. Interacts with FASLG.

Tissue Specificity:
Expressed in brain, lung, kidney, and testis.

Similarity:
Contains 1 FCH domain.
Contains 1 Rho-GAP domain.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 57522 Human

Entrez Gene: 117600 Mouse

Entrez Gene: 314903 Rat

Omim: 606523 Human

SwissProt: Q7Z6B7 Human

SwissProt: Q91Z69 Mouse

Unigene: 210751 Human

Unigene: 593803 Human

Unigene: 288698 Mouse

Unigene: 208903 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 91色片| 国产精华最好的产品入口 | 国产免费午夜福利片在线 | 国产性一交一乱一伦一色一情 | 藏精阁成人免费观看在线视频 | 久久一精品| 国产日韩视频在线播放 | 国产在线观看香蕉视频网 | 国色天香免费视频日本 | 命带桃花1987在线 | 日本欧美一区 | 欧美成人精品一区二区男人看 | 亚洲成AV人片一区二区密柚 | 成人毛片在线 | 欧美日韩无 | 成人av中文解说水果派在线观看 | 天天躁日日躁狠狠躁aab吃奶 | 日韩精品无码免费专区午夜 | 一女多男两根同时进去性视频 | 成在人线AV无码免费高潮喷水 | 一本一道波多野结衣av黑人 | 亚洲精品久久久一区二区图片 | 国产免费一级特黄真人视频 | 蜜桃视频在线观看一区 | 四虎影音 | 国内自拍片 | 国产精品人人妻人人爽人人牛 | 131mm亚洲国产精品久久 | 妺妺窝人体色777777 | 国产精品96久久久久久又黄又硬 | 亚洲v在线 | YYYY111111少妇影院 | 日本真人添下面视频免费 | 97热在线观看 | 免费无码成人AV片在线在线播放 | 久久日韩激情一区二区三区四区 | 男男网站18禁免费 | 国产女同一区二区在线 | 亚洲三区一区 | 久热在线播放中文字幕 | 亚洲AV无码成人专区 |