97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
h成人动漫在线,91新视频在线观看,亚洲伦无码中文字幕另类
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Kir4.1/PE-Cy5.5 Conjugated antibody (bs-2084R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2084R-PE-Cy5.5
英文名稱 Rabbit Anti-Kir4.1/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的細胞內流鉀通道蛋白Kir4.1抗體
別    名 ATP dependent inwardly rectifying potassium channel Kir4.1; ATP sensitive inward rectifier potassium channel 10; ATP-dependent inwardly rectifying potassium channel Kir4.1; ATP-sensitive inward rectifier potassium channel 10; BIRK10; Glial ATP dependent inwardly rectifying potassium channel KIR4.1; Inward rectifier K(+) channel Kir1.2; Inward rectifier K+ channel KIR1.2; Inwardly rectifying potassium channel Kir1.2; inwardly rectifying subfamily J member 10; KCNJ 10; Kcnj10; KCNJ13 PEN; KIR1.2; KIR4.1; Potassium channel; Potassium channel inwardly rectifying subfamily J member 10; Potassium inwardly rectifying channel subfamily J member 10; SESAME; IRK10_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  通道蛋白  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Kir4.1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Down’s syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas. The gene encoding human KIR5.1 maps to chromosome 17.

Function:
May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.

Subunit:
Seems to form heterodimer with Kir5.1/KCNJ16. Interacts with INADL

Subcellular Location:
Membrane; Multi-pass membrane protein.

DISEASE:
Defects in KCNJ10 are the cause of seizures-sensorineural deafness-ataxia-mental retardation-electrolyte imbalance (SESAME) [MIM:612780]. A complex disorder characterized by generalized seizures with onset in infancy, delayed psychomotor development, ataxia, sensorineural hearing loss, hypokalemia, metabolic alkalosis, and hypomagnesemia.

Similarity:
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ10 subfamily.

Database links:

Entrez Gene: 3766 Human

Entrez Gene: 16513 Mouse

Entrez Gene: 29718 Rat

Omim: 602208 Human

SwissProt: P78508 Human

SwissProt: Q9JM63 Mouse

SwissProt: P49655 Rat

Unigene: 408960 Human

Unigene: 254563 Mouse

Unigene: 10196 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久久久人妻精品区一三寸 | www香蕉 | 好深好湿好硬顶到了好爽 | 日韩精品国产自在久久现线拍 | 91精品国产综合久久男男 | 国产一级二级视频 | 伊人青青久久 | 亚卅在线有码无码免费 | 欧美美女久久 | 一级做a爰片性色毛片99高清 | 亚洲精品久久无码AV片亚洲有色 | 久久爆操| 在线精品亚洲一区二区动态图 | jizz成熟丰满日本少妇 | 伊人狠狠干 | 中文字幕日韩精品视频一区视频二区 | 亚洲人av在线影院 | 91视频.www| 亚洲国产果冻传媒av在线观看 | 国产精品毛片一区视频播 | 少妇激情一区二区三区视频 | 熟妇人妻无乱码中文字幕 | 日日噜狠狠噜天天噜AV | 绿帽在线 | 国产AV无码精品国产精品 | 超碰福利在线观看 | 精品成人私密视频 | 亚洲中文久久精品81 | 麻豆传媒视频在线播放 | 久久中文高清 | 少妇被粗大的猛烈进出动态图片 | 久久处女视频 | JAVASCRIPT中国免费 | 欧美肥妇毛多水多bbxx水蜜桃 | 国产精品日韩AV在线播放 | 国产一区福利在线 | 国产一区国产二区在线观看 | 国产乱码精品 | 欧美自拍区 | 在线观看免费黄色小视频 | GOGOGO免费高清视频3 |