97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日本无遮羞调教打屁股,国产伦精品一区二区三区照片,狠狠色噜噜狠狠米奇777
Rabbit Anti-CD299/Biotin Conjugated antibody (bs-10064R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-10064R-Bio
英文名稱 Rabbit Anti-CD299/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的CD299抗體
別    名 C type lectin domain family 4 member M; C type lectin domain family 4, member M; C-type lectin domain family 4, member M; CD209 antigen like protein 1; CD209 antigen-like; CD209L; CD209L1; CD299 antigen; CLEC4M; DC SIGN related protein; DC SIGN2; DC SIGNR; DC-SIGN related protein; DC-SIGN2; DC-SIGNR; DCSIGN-related protein; DCSIGNR; dendritic cell specific ICAM-3-grabbing nonintegrin 2; Dendritic cell-specific ICAM-3-grabbing non-integrin 2; HP10347; L SIGN; Liver/lymph node specific ICAM 3 grabbing nonintegrin; Liver/lymph node-specific ICAM3-grabbing nonintegrin; LSIGN; Mannose binding C-type lectin DC-SIGNR; MGC129964; MGC47866; CLC4M_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD299
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Dendritic cells (DC) play a primary role in the immune system as antigen presenting cells. A key molecule, dendritic cell specific ICAM3 grabbing nonintegrin (DC SIGN1), is involved in regulating interactions between DC and resting T cells, including antigen presentation to T cells and enhancement of transinfection of CD4+ T cells by HIV 1. Efforts to identify additional type II membrane proteins resulted in the isolation of a related molecule named CD299, also known as DC SIGNR (DC SIGN Related), DC SIGN2, CD209L, and L SIGN (liver/lymph nodespecific ICAM3 grabbing nonintegrin). CD299 is located on Human chromosome 19p13.3 and shares 73-80% amino acid identity with DC SIGN1. Its structure is similar to DC SIGN1 and therefore binds mannose residues in a calcium dependent fashion, including ICAM3 and HIV 1 gp120. CD299 is polymorphic, since allelic variations of the exon 4 encoded sequence have been isolated. This is further supported by a study demonstrating the ability to isolate a large repertoire of CD299 transcripts largely the result of alternative splicing of the 7 coding exons. CD299 is primarily transcribed in the liver and lymph nodes but not in monocyte derived DC. Expression of CD299 is restricted to endothelial cells derived from liver sinusoids, lymph nodes sinuses, and capillaries, although variable expression in placenta and some monocytic cell lines has also been reported, including both membrane and soluble isoforms of the protein.

Function:
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens, including HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus protein S. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. Is presumably a coreceptor for the SARS coronavirus.

Subunit:
Homotetramer. Binds to many viral surface glycoproteins such as HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus S protein.

Subcellular Location:
Isoform 1, 2, 3: Cell membrane; Single-pass type II membrane protein (Potential). Isoform 5, 6, 7, 10: Secreted (Potential).

Tissue Specificity:
Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells.

Similarity:
Contains 1 C-type lectin domain.

Database links:

Entrez Gene: 10332 Human

Omim: 605872 Human

SwissProt: Q9H2X3 Human

Unigene: 421437 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 亚洲国产成人精品女人久 | 2024国产精品自拍 | 国产精成人品日日拍夜夜免费 | 午夜秒播 | 天天做天天爱夜夜爽女人爽 | 日本片成人在线观看 | 成人活性生交大片免费看 | 扒开双腿猛进入在线观看 | 91老司机福利在线视频 | 91短视频网站 | 欧美激情视频一区二区 | 国产精品久久精品 | 欧美老熟妇乱子 | 丝袜美腿精品国产一区 | 无码国产玉足脚交极品网站 | 日本二三本的区别免费 | 欧美一级黄色网 | 亚洲综合在线一区 | 美国黄色片子 | 亚洲成AV人片在线观看橙子 | www.好色| 日韩高清www | 亚洲国产午夜精品 | 92国产精品偷窥熟女精品视频 | 人妻无码中文专区久久综合 | 国产精妇在线观看第一区 | 亚洲综合图片网 | av黄色在线 | 成人免费看98影视mp4 | 日本天堂视频在线观看 | 无码三级香港经典三级在线视频 | 国产亚洲91 | 欧美特黄aaa | 91兔费视频| 婷婷国产一区综合久久精品 | 成人A片产无码免费奶头 | 天天看片夜夜爽 | 久久免费观看少妇a级毛片 正能量免费网站WWW正能量免费 | 91精品在线免费视频 | 亚洲精品无码久久久久去Q 国产精选一级毛片 | 白丝老师在我胯下娇喘视频 |