97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
snh48国产大片永久,欧美日韩国产限制,色人阁导航
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CD299/FITC Conjugated antibody (bs-10064R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-10064R-FITC
英文名稱 Rabbit Anti-CD299/FITC Conjugated antibody
中文名稱 FITC標記的CD299抗體
別    名 C type lectin domain family 4 member M; C type lectin domain family 4, member M; C-type lectin domain family 4, member M; CD209 antigen like protein 1; CD209 antigen-like; CD209L; CD209L1; CD299 antigen; CLEC4M; DC SIGN related protein; DC SIGN2; DC SIGNR; DC-SIGN related protein; DC-SIGN2; DC-SIGNR; DCSIGN-related protein; DCSIGNR; dendritic cell specific ICAM-3-grabbing nonintegrin 2; Dendritic cell-specific ICAM-3-grabbing non-integrin 2; HP10347; L SIGN; Liver/lymph node specific ICAM 3 grabbing nonintegrin; Liver/lymph node-specific ICAM3-grabbing nonintegrin; LSIGN; Mannose binding C-type lectin DC-SIGNR; MGC129964; MGC47866; CLC4M_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD299
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Dendritic cells (DC) play a primary role in the immune system as antigen presenting cells. A key molecule, dendritic cell specific ICAM3 grabbing nonintegrin (DC SIGN1), is involved in regulating interactions between DC and resting T cells, including antigen presentation to T cells and enhancement of transinfection of CD4+ T cells by HIV 1. Efforts to identify additional type II membrane proteins resulted in the isolation of a related molecule named CD299, also known as DC SIGNR (DC SIGN Related), DC SIGN2, CD209L, and L SIGN (liver/lymph nodespecific ICAM3 grabbing nonintegrin). CD299 is located on Human chromosome 19p13.3 and shares 73-80% amino acid identity with DC SIGN1. Its structure is similar to DC SIGN1 and therefore binds mannose residues in a calcium dependent fashion, including ICAM3 and HIV 1 gp120. CD299 is polymorphic, since allelic variations of the exon 4 encoded sequence have been isolated. This is further supported by a study demonstrating the ability to isolate a large repertoire of CD299 transcripts largely the result of alternative splicing of the 7 coding exons. CD299 is primarily transcribed in the liver and lymph nodes but not in monocyte derived DC. Expression of CD299 is restricted to endothelial cells derived from liver sinusoids, lymph nodes sinuses, and capillaries, although variable expression in placenta and some monocytic cell lines has also been reported, including both membrane and soluble isoforms of the protein.

Function:
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens, including HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus protein S. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. Is presumably a coreceptor for the SARS coronavirus.

Subunit:
Homotetramer. Binds to many viral surface glycoproteins such as HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus S protein.

Subcellular Location:
Isoform 1, 2, 3: Cell membrane; Single-pass type II membrane protein (Potential). Isoform 5, 6, 7, 10: Secreted (Potential).

Tissue Specificity:
Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells.

Similarity:
Contains 1 C-type lectin domain.

Database links:

Entrez Gene: 10332 Human

Omim: 605872 Human

SwissProt: Q9H2X3 Human

Unigene: 421437 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 91天仙tv国产福利精品 | 宝宝好涨水快流出来免费视频 | 性色AV一区二区三区无码 | 无码人妻精品一区二区在线视频 | 久久青青草原国产精品最新片 | 久久精品无码专区免费东京热 | 男人插女人免费视频 | 红尘影院手机在线观看 | 91caoporn超碰最新地址 | 久久久人精午夜精国 | 强壮的公次次弄得我高潮a片日本 | 日本十八禁视频无遮挡 | 无码AV无码一区二区桃花岛 | 久久久91精品国产一区二区精品 | 国产成熟人妻换╳╳╳╳ | 久久精品亚洲男人的天堂 | 狠狠躁夜夜躁人人躁婷婷视频 | 91性视频 | 国产在线观看福利 | 久久青青草原国产精品最新片 | 成人片黄网站色大片免费毛片 | 亚洲欧美日韩中文高清WWW777 | japanese国产乱在线播放 | 亚洲爆乳中文字幕无码专区网站 | 特级做a爰片免费看一区 | 青青网视频 | 久久众筹精品私拍模特 | 国产精品免费网站 | 日韩一本在线 | 最近更新中文字幕手机版 | 欧美变态口味重另类在线视频 | 无码人妻精一区二区三区 | 99久久综合狠狠综合 | 在线黄色观看 | 欧美日韩国产限制 | 国产91精品一区二区三区四区 | 免费AV一区二区三区3ATV | 亚洲视频二区在线观看 | 天堂国产一区 | 亚洲综合站 | 天堂а在线中文在线新版 |