97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
久久精品国产99国产精品澳门,欧美大片www,99热久久成人免费频精品2
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Afadin/I Afadin/AP Conjugated antibody (bs-2754R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2754R-AP
英文名稱 Rabbit Anti-Afadin/I Afadin/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的絲狀肌動蛋白結合蛋白抗體
別    名 AF 6; AF6; AFAD_HUMAN; Afadin; ALL1-fused gene from chromosome 6 protein; FLJ34371; MLLT 4; MLLT4; Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog Drosophila) translocated to 4; Myeloid/lymphoid or mixed lineage leukemia translocated to 4; Protein AF 6; Protein Af-6; Protein AF6; RP3 431P23.3; 5033403D15Rik; Gm314; I-afadin; Mllt4; S-afadin.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  信號轉導  細胞粘附分子  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 136kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AF6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Afadin is a cell-cell adherens junction F-actin binding multidomain protein. Two splice variants of afadin have been described: l-afadin, which is ubiquitously expressed, and the smaller s-afadin, which is abundantly expressed in neural tissue. l-Afadin contains one PDZ domain near its middle followed by three proline-rich and one F-actin-binding region at the carboxyl-terminal. l/s-Afadin is localized to cell-cell junctions and binds several cytoplasmic proteins such as the small GTPase Ras, the tight junction protein ZO-1, and the vinculin binding protein ponsin/SH3P12.

Function:
Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton.

Subunit:
Homodimer. Interacts with F-actin, nectin and PVRL3/nectin-3. Essential for the association of nectin and E-cadherin. Isoform 1/s-afadin does not interact with F-actin. Interacts with ZO-1 and occludin, but probably in an indirect manner. Interacts with RIT1 and RIT2 (By similarity). Interacts with NRXN1 and BCR.

Subcellular Location:
Cell junction, adherens junction. Note=Not found at cell-matrix AJs.

DISEASE:
Note=A chromosomal aberration involving MLLT4 is associated with acute leukemias. Translocation t(6;11)(q27;q23) with MLL/HRX. The result is a rogue activator protein.

Similarity:
Contains 1 dilute domain.
Contains 1 FHA domain.
Contains 1 PDZ (DHR) domain.
Contains 2 Ras-associating domains

Database links:

Entrez Gene: 4301 Human

Entrez Gene: 17356 Mouse

Entrez Gene: 26955 Rat

Omim: 159559 Human

SwissProt: P55196 Human

SwissProt: Q9QZQ1 Mouse

SwissProt: O35889 Rat

Unigene: 614974 Human

Unigene: 644024 Human

Unigene: 708726 Human

Unigene: 728849 Human

Unigene: 59167 Mouse

Unigene: 58 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 龙珠z免费观看国语版 | 精品人妻中文字幕有码在线 | wwwwwww黄| 国产日本一区二区 | 亚洲aⅴ久久精品蜜桃小仓由菜 | 中文字幕中文字幕在线中文字幕三区 | 国产精品综合在线观看 | 国产精品无 | 日韩一级淫片 | 久久精品一二 | 人妻无码AV一区二区三区精品 | 国产一区二区免费在线观看 | 一区二区三区四区视频免费观看 | 欧美GAY猛男GAYA片18禁 | 亚洲AV无码精品色午夜蜜芽 | 色哟哟~日韩精品 | 久久99久久久 | 欧美激情第五页 | 久久porn| 无码aⅴ免费中文字幕久久 国产精品1234 | 成人激情av | 九九热只有精品 | 免费追剧网址 | 国产成人在线观看网站 | 日本不卡免费一区二区三区综合久久 | www.av黄 | 日本免费一区二区三区高清视频 | 漂亮人妻中文字幕丝袜 | 999久久免费精品国产 | 欧美日韩综合一区二区在线观看视频 | 中文字幕一区在线观看视频 | 日韩欧美的一区二区 | 久久亚洲国产视频 | 国产精品天天狠天天看 | 国产在线不卡精品网站 | 女人下边被添全过程A片图片 | 正能量免费网站WWW正能量免费 | 国产91精品亚洲一区二区三区 | 亚洲熟妇久久精品 | 白丝美女被操黄色视频国产免费 | 日韩精品久久久久久中文字幕8 |