97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
爆乳放荡的女教师bd,一本之道色综合网站,免费看黄色一级视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Phospho-cdc25C (Ser216)/BF350 Conjugated antibody (bs-3096R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3096R-BF350
英文名稱 Rabbit Anti-Phospho-cdc25C (Ser216)/BF350 Conjugated antibody
中文名稱 BF350標記的磷酸化細胞分裂周期蛋白25C抗體
別    名 cdc25C(Phospho-Ser216); cdc25C(Phospho Ser216); cdc25C(Phospho S216); CDC 25; Cdc 25C; CDC25; CDC25C; Cell division cycle 25 homolog C; Cell Division Cycle 25C; Cell Division Cycle 25C; Cell division cycle 25C protein; Dual specificity phosphatase Cdc25C; M phase inducer phosphatase 3; M-phase inducer phosphatase 3; Mitosis inducer CDC25; MPIP3; MPIP3_HUMAN; Phosphotyrosine phosphatase.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  染色質和核信號  信號轉導  細胞周期蛋白  激酶和磷酸酶  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human cdc25C around the phosphorylation site of Ser216
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008]

Function:
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.

Subunit:
Interacts with HIV-1 Vpr, thereby inactivating CDC25C phosphatase activity. Interacts with MAPK14 and 14-3-3 proteins.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated by CHEK1 and MAPK14 at Ser-216. This phosphorylation creates a binding site for 14-3-3 protein and inhibits the phosphatase. Phosphorylated by PLK4. Phosphorylated by PLK1, leading to activate the phosphatase activity. Phosphorylation by PLK3 at Ser-191 promotes nuclear translocation. Ser-198 is a minor phosphorylation site. Was initially reported to be phosphorylated by PLK3 at Ser-216 (PubMed:10557092). However, such phosphorylation by PLK3 was not confirmed by other groups. Phosphorylation at Thr-48, Thr-67, Ser-122, Thr-130, Ser-168 and Ser-214 occurs at G2 and G2-M transition and is probably catalyzed by CDK1. Ser-168 phosphorylation levels are lower than those at the other 5 CDK1 sites. Phosphorylation by CDK1 leads to increased activity.

Similarity:
Belongs to the MPI phosphatase family.
Contains 1 rhodanese domain.

Database links:

Entrez Gene: 995 Human

Omim: 157680 Human

SwissProt: P30307 Human

Unigene: 656 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CDC25家族的組成哺乳動物中CDC25家族一共包括3種同源異構體(CDC25A、CDC25B、CDC25C),約有50%的序列同源,是一組在細胞周期調控中發揮巨大作用的蘇/酪氨酸雙功能酶 。不同的CDC25家族蛋白在細胞周期中的作用時相亦有差異,CDC25A和CDC25C分別在S期和M期發揮主要作用。
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 免费黄色网址在线观看 | 四川少妇搡BBW搡BBBB | 精品久久中文字幕97 | 91中文字幕在线视频 | 色香蕉久久| 国产手机在线αⅴ片无码观看 | 日韩亚洲区字幕 | 青青草久久| 亚洲性AV网站 | 4虎最新地址| 日本男人天堂 | 在线观看无码AV网站永久免费 | 人妻无码中文字幕永久在线 | 狠狠操社区 | 国产精品一区二区免费久久精品 | 91久久精品国产91久久性色也 | 韩国毛片在线 | 亚洲黄色网页 | 绝顶高潮videos | 欧美日韩高清一区二区三区 | 国产精品久久一区主播 | 恋爱的味道1在线 | 午夜香吻高清观看视频在线 | 精品在线观看一区二区 | 亚洲中文久久精品无码软件 | 少妇翘臀亚洲精品av图片 | 龙珠z免费观看国语版 | 男人猛躁女人免视频 | 亚洲视频在线看 | 日韩欧美中文字幕在线四区 | 久久超碰精品 | 亚洲国产影院av久久久久 | 中文理论片 | 日本高清视频在线观看 | 操操综合网 | 亚洲丁香婷婷久久一区二区 | 日韩中文字幕亚洲欧美 | 爱爱免费看 | 篱笆女人狗电视连续剧第一部 | 国产91xxx在线观看大全 | 久久九九热 |