97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
久久五月丁香合缴情网,国产va视频,男女免费视频观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-cofilin/Cy3 Conjugated antibody (bs-2759R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2759R-Cy3
英文名稱 Rabbit Anti-cofilin/Cy3 Conjugated antibody
中文名稱 Cy3標記的絲切蛋白抗體
別    名 18 kDa phosphoprotein; CFL 1; CFL; CFL1; Cofilin 1; Cofilin 1 non muscle; Cofilin non muscle isoform; p18; COF1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  生長因子和激素  轉錄調節因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, Chicken, Dog, Pig, Cow, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Synthetic peptide from the human cofilin conjugated to KLH
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004].

Function:
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Subunit:
Can bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is a major component of intranuclear and cytoplasmic actin rods.

Subcellular Location:
Nucleus matrix. Cytoplasm, cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.

Tissue Specificity:
Widely distributed in various tissues.

Post-translational modifications:
Inactivated by phosphorylation on Ser-3. Phosphorylated on Ser-3 in resting cells. Dephosphorylated by PDXP/chronophin; this restores its activity in promoting actin filament depolymerization. The phosphorylation of Ser-24 may prevent recognition of the nuclear localization signal.

Similarity:
Belongs to the actin-binding proteins ADF family.
Contains 1 ADF-H domain.

Database links:

Entrez Gene: 1072 Human

Entrez Gene: 12631 Mouse

Entrez Gene: 29271 Rat

Omim: 601442 Human

SwissProt: P23528 Human

SwissProt: P18760 Mouse

SwissProt: P45592 Rat

Unigene: 170622 Human

Unigene: 329655 Mouse

Unigene: 11675 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

絲切蛋白(cofilin)是細胞骨架塑形的重要調節因素,其主要功能是分解肌動蛋白微絲和增加肌動蛋白單體從肌動蛋白微絲的末端解離的速度,從而促進肌動蛋白微絲的循環,是目前為止已發現的肌動蛋白結合蛋白家族中唯一能夠改變肌動蛋白微絲扭曲結構的蛋白.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 日韩人妻精品一区二区三区视频 | 国产传媒第一页 | 激情国产AV做激情国产爱 | 色情久久久AV熟女人妻网站 | 2023国精产品一二二线免费 | 草草亚洲视频 | 免费一区二区在线观看 | 国产成人a在线视频免 | 精品乱码一区二区三四区 | 亚洲色就色成人综合网 | av线网| 日韩视频一区二区三区在线观看 | 国产精品毛片一区视频播 | 国内精品久久久久国产盗摄 | 欧美成人A片无码免费 | 国产对白女主播勾搭野战在线 | 免费福利在线观看 | 精品看片 | 美女视频三区 | 国内精品久久久久影院免费 | 性色av一区二区怡红 | 日韩高清二区 | 亚洲а∨天堂久久精品2021 | 一区二区久久精品 | 亚洲精品无码久久久久AV老牛 | 午夜激情综合网 | 国产福利一区二区精品秒拍 | 伊人精品在线观看 | 亚洲欧美国产精品久久久久 | 少妇大叫又粗又大太爽A片 heyzo朝桐光一区二区 | 啪啪网址大全 | 国产精品高清视亚洲乱码 | 国产小视频a | 亚洲第一免费视频 | 国产CHINESEHDXXXX 亚洲AV无码国产在丝袜线观看 | 亚洲熟女色情网中文字幕 | 无码精品人妻一区二区三区老牛 | 一级少妇性生话片 | 女人被狂躁的高潮免费视频 | 国产成在线观看免费视频成本人 | 久久久精品小视频 |