97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产人妖ts重口系列网站观看,欧美一区二区免费视频,欧美性另类69xxxx最新章节
Rabbit Anti-cofilin/PE Conjugated antibody (bs-2759R-PE)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-2759R-PE
英文名稱 Rabbit Anti-cofilin/PE Conjugated antibody
中文名稱 PE標(biāo)記的絲切蛋白抗體
別    名 18 kDa phosphoprotein; CFL 1; CFL; CFL1; Cofilin 1; Cofilin 1 non muscle; Cofilin non muscle isoform; p18; COF1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  生長(zhǎng)因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat,  (predicted: Mouse, Chicken, Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Synthetic peptide from the human cofilin conjugated to KLH
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004].

Function:
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Subunit:
Can bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is a major component of intranuclear and cytoplasmic actin rods.

Subcellular Location:
Nucleus matrix. Cytoplasm, cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.

Tissue Specificity:
Widely distributed in various tissues.

Post-translational modifications:
Inactivated by phosphorylation on Ser-3. Phosphorylated on Ser-3 in resting cells. Dephosphorylated by PDXP/chronophin; this restores its activity in promoting actin filament depolymerization. The phosphorylation of Ser-24 may prevent recognition of the nuclear localization signal.

Similarity:
Belongs to the actin-binding proteins ADF family.
Contains 1 ADF-H domain.

Database links:

Entrez Gene: 1072 Human

Entrez Gene: 12631 Mouse

Entrez Gene: 29271 Rat

Omim: 601442 Human

SwissProt: P23528 Human

SwissProt: P18760 Mouse

SwissProt: P45592 Rat

Unigene: 170622 Human

Unigene: 329655 Mouse

Unigene: 11675 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

絲切蛋白(cofilin)是細(xì)胞骨架塑形的重要調(diào)節(jié)因素,其主要功能是分解肌動(dòng)蛋白微絲和增加肌動(dòng)蛋白單體從肌動(dòng)蛋白微絲的末端解離的速度,從而促進(jìn)肌動(dòng)蛋白微絲的循環(huán),是目前為止已發(fā)現(xiàn)的肌動(dòng)蛋白結(jié)合蛋白家族中唯一能夠改變肌動(dòng)蛋白微絲扭曲結(jié)構(gòu)的蛋白.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 一区两区三区四区乱码国产精品 | 成人免费视频xbxb入口 | 日本一区二区久久精品 | 四虎影视库www111we | 我的妺妺h伦浴室无码视频 国产激情无码视频在线播放性色 | 老司机伊人网 | 一人之下2在线观看 | 日本乱妇日本乱妇18 | 99精品观看| 99激情网 | 秋霞福利网 | 欧美aaaaxxxxx精品 | 精品无码日韩一区二区三区不卡 | 第一区视频 | 18日本xxxxxxxxx95| 久久这里精品国产99丫e6 | 人妻丰满熟妇AV无码区乱 | 少妇人妻陈艳和黑人教练 | 天天综合网页在线观看 | 日本中出视频 | 亚洲精品乱码久久久久 | 中文字幕一区二区三区乱码在线 | 天天做天天爱天天爽综合网 | 视频二区三区 | 久久久6精品成人午夜51777 | 99热6这里只有精品 国产一区=区 | 综合在线视频 | 狠狠躁躁夜夜躁波多野结依 | 一区二区福利 | 天天爽夜夜爽人人爽QC | 久久无码精品一区二区三区 | 亚洲3p激情在线观看 | 永久免费A∨片在线观看 | 日本亚洲欧洲色α | 欧美肥臀大屁股MAGNET | 噜噜噜在线观看免费视频日本 | 911色_911色sss主站色播 | 国产美女视频a级做爰色戎 一本久久A精品一区二区 | 日日射影院 | 波多野结衣伦理在线观看 | 不卡av免费在线观看 |