97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
成人免费网站入口,性欧美VIDEOFREE高清精品,亚洲黄色a
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Phospho-Glycogen synthase 1(Ser641)/Cy7 Conjugated antibody (bs-3190R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3190R-Cy7
英文名稱 Rabbit Anti-Phospho-Glycogen synthase 1(Ser641)/Cy7 Conjugated antibody
中文名稱 Cy7標記的磷酸化葡萄糖合成酶1抗體
別    名 Glycogen synthase 1 (phospho S641); Glycogen synthase 1 (phospho Ser641); p-Glycogen synthase 1 (S641); Glycogen synthase 1 (muscle); Glycogen synthase 1; GSY; GYS; GYS1; EC 2.4.1.11; Glycogen synthase1; GYS 1; Starchsynthase muscle; UDP glucose glycogen glucosyltransferase; GYS1_HUMAN; Glycogen [starch] synthase, muscl.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領域 腫瘤  免疫學  信號轉導  轉錄調節(jié)因子  激酶和磷酸酶  合成與降解  糖尿病  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Cat, )
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 85kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Glycogen synthase 1 around the phosphorylation site of Ser641
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70% identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.

Function:
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

Subunit:
Interacts with GYG1.

Post-translational modifications:
Phosphorylation at Ser-8 by AMPK inactivates the enzyme activity. Primed phosphorylation at Ser-657 (site 5) by CSNK2A1 and CSNK2A2 is required for inhibitory phosphorylation at Ser-641 (site 3a), Ser-645 (site 3b), Ser-649 (site 3c) and Ser-653 (site 4) by GSK3A an GSK3B (By similarity). Phosphorylated at Ser-641 by PASK, leading to inactivation; phosphorylation by PASK is inhibited by glycogen. Dephosphorylation at Ser-641 and Ser-645 by PP1 activates the enzyme.

DISEASE:
Defects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; also known as muscle glycogen synthase deficiency. GSD0b is a metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.

Similarity:
Belongs to the glycosyltransferase 3 family.

Database links:

Entrez Gene: 2997 Human

Entrez Gene: 14936 Mouse

Entrez Gene: 690987 Rat

Omim: 138570 Human

SwissProt: P13807 Human

SwissProt: Q8VEB0 Mouse

SwissProt: Q9Z1E4 Mouse

SwissProt: A2RRU1 Rat

Unigene: 386225 Human

Unigene: 275654 Mouse

Unigene: 95278 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产精品亚洲午夜不卡 | 欧美精品四区 | WWW国产精品内射老师 | 特大黄色片 | 国产精品无码午夜福利 | 永久黄网站色视频免费 | 在线aⅴ免费 | 前夜40集连续剧免费观看国语高清 | 狠狠操图片 | 黑人狂躁日本妞一区二区三区 | 天天躁日日躁狠狠躁欧美老妇小说 | 久久久久亚洲综合 | 欧美不卡一区 | 麻豆av资源 | 精品国产一区二区三区色欲 | 亚洲毛片在线视频 | 久久中国精品 | 欧美性暴力变态XXXX | 午夜无码乱码在线观看 | 亚洲欧洲老熟女AV | JIZZJIZZ亚洲日本少妇 | 天天躁日日躁aaaa视频 | H无码精品动漫在线观看导航 | 桃子视频在线观看免费视频网 | 久www| 国产精品久久一区主播 | 给我免费观看片在线观看 | 天天躁日日躁aaaa视频 | 成人av色 | 久久爱综合网 | 国产男小鲜肉同志免费 | 亚洲成av人片在线观看无码不卡 | 中文无码一区二区视频在线播放 | 伊人中文字幕在线观看 | 每日更新在线观看AV | 亚洲精品熟女国产 | 久久久无码精品成人A片小说 | 四虎影视在线影院在线观看 | av资源免费观看 | 级R片内射在线视频播放 | 玩弄JAPAN白嫩少妇HD小说 |