97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
小荡货好紧好爽h护士在线观看,国产一精品一AV一免费爽爽,两个人看的www在线观看视频
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Phospho-MKK3(Ser218) + MKK6(Ser207) /PE Conjugated antibody (bs-3274R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3274R-PE
英文名稱 Rabbit Anti-Phospho-MKK3(Ser218) + MKK6(Ser207) /PE Conjugated antibody
中文名稱 PE標記的磷酸化絲裂原活化蛋白激酶MKK3/6抗體
別    名 MKK3(Phospho-Ser218); MAP Kinase Kinase 3; Dual specificity mitogen activated protein kinase kinase 3; ERK kinase 3; MAP kinase kinase 3; MAP2K 3; MAPK ERK kinase 3; MAPK kinase 3; MAPKK 3; MAPKK3; MEK 3; MEK3; Mitogen activated protein kinase kinase 3; MKK 3; MKK3; mMKK 3b; mMKK3b; MPK 3; PRKMK 3; PRKMK3; Protein kinase mitogen activated kinase 3; SKK2; zMKK 3; MP2K3_HUMAN; MP2K6_HUMAN  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  信號轉(zhuǎn)導(dǎo)  細胞凋亡  生長因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human MKK3 around the phosphorylation site of Ser218
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.

Function:
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.

Subunit:
Binds to DYRK1B/MIRK and increases its kinase activity. Part of a complex with MAP3K3, RAC1 and CCM2. Interacts with ARRB1. Interacts with Yersinia yopJ.

Tissue Specificity:
Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.

Post-translational modifications:
Autophosphorylated. Phosphorylation on Ser-218 and Thr-222 by MAP kinase kinase kinases regulates positively the kinase activity. Phosphorylated by TAOK2.
Yersinia yopJ may acetylate Ser/Thr residues, preventing phosphorylation and activation, thus blocking the MAPK signaling pathway.

DISEASE:
Note=Defects in MAP2K3 may be involved in colon cancer.

Similarity:
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 5606 Human

Entrez Gene: 26397 Mouse

Entrez Gene: 303200 Rat

Omim: 602315 Human

SwissProt: P46734 Human

SwissProt: O09110 Mouse

Unigene: 514012 Human

Unigene: 18494 Mouse

Unigene: 100064 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 无码人妻一区二区免费AV | 玖草影院| 精品毛片| 日本hdxxxx少妇1819 | 成人精品综合 | 国内精品国产成人国产三级李采潭 | 无码少妇高潮喷水A片免费 欧美性xxxx视频 | 久久国产亚洲日韩 | 香蕉视频导航 | 少妇被爽到高潮动态图 | 国产精品国产三级国产普通话三级 | av在线免费观看网站 | 四虎首页 | 亚洲精品久久无码AV片亚洲有色 | 少妇高潮呻吟在线观看 | 国产欧美日本一区二区三区 | 熟妇人妻无乱码中文字幕 | 亚洲瑟瑟 | 女人被添全过程A片久久AV | 年轻母亲4在线 | ye321夜色资源最新地址 | 免费在线看片网站 | JIZZ成熟丰满韩国女人少妇 | 成人手机在线视频 | 波多野结衣高潮喷水在线观看 | 午夜精品一区二区三区三上悠亚 | 国产剧情无码播放在线观看 | 亚洲有吗在线观看 | 日本久色 | 国产精品扒开腿做爽爽爽A片唱戏 | 国产精品久久久久久一区二区三区 | 日本一级a毛片免费观看 | 老熟女激烈的高潮 | 亚洲精品97久久中文字幕无码 | 精品人妻无码一区二区三区4 | 九九热线视频只有这里最精品 | 国产妓女一级在线视频 | 男人被口爽还是啪啪爽 | 影音先锋女人AV鲁色资源网久久 | 精品在线免费看 | 99久久夜色精品国产亚洲 |