97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
粉嫩小泬无遮挡久久久久久,国产又粗又黄又爽的A片精华液,韩国毛片免费观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-HSD11B2/PE-Cy5 Conjugated antibody (bs-3618R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3618R-PE-Cy5
英文名稱 Rabbit Anti-HSD11B2/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標記的羥基類固醇脫氫酶11β2抗體
別    名 Corticosteroid 11 beta dehydrogenase isozyme 2; 11 beta HSD2; 11 beta hydroxysteroid dehydrogenase type 2; 11 DH2; AME; AME1; HSD11K; HSD2; Hydroxysteroid 11 beta dehydrogenase 2; Hydroxysteroid 11 beta dehydrogenase isoenzyme 2; NAD dependent 11 beta hydroxysteroid dehydrogenase; SDR9C3; Short chain dehydrogenase/reductase family 9C, member 3.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  信號轉導  細胞凋亡  轉錄調節因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat, Horse,  (predicted: Human, Dog, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HSD11B2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension. [provided by RefSeq, Feb 2010]

Function:
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

Subunit:
Interacts with ligand-free cytoplasmic NR3C2.

Subcellular Location:
Microsome. Endoplasmic reticulum.

Tissue Specificity:
Found in placenta, kidney, pancreas, prostate, ovary, small intestine and colon.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Database links:

Entrez Gene: 282434 Cow

Entrez Gene: 3291 Human

Entrez Gene: 15484 Mouse

Entrez Gene: 396948 Pig

Entrez Gene: 25117 Rat

Omim: 218030 Human

SwissProt: O77667 Cow

SwissProt: P80365 Human

SwissProt: P51661 Mouse

SwissProt: P51976 Rabbit

SwissProt: P50233 Rat

SwissProt: P50168 Sheep

Unigene: 1376 Human

Unigene: 5079 Mouse

Unigene: 10186 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

[DISEASE] Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME) [MIM:218030]. An autosomal recessive form of low-renin hypertension. It is usually diagnosed within the first years of life and is characterized by polyuria and polydipsia, failure to thrive, hypernatremia, severe hypertension with low renin and aldosterone levels, profound hypokalemia with metabolic alkalosis, and most often nephrocalcinosis.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 黄色美女一级片 | 亚洲人成网站在线观看妞妞网 | 性欧美人与zozoxxxx视频 | 狠狠做深爱婷婷久久综合一区 | 国产成人精品综合久久久久99 | 99热这里只有精品久久 | 欧美精产国品一二三产品 | 国产精品超碰 | 正在播放国产对白孕妇作爱 | 四虎国产精品成人 | 成人午夜视频精品一区 | 一区2区3区在线看 | 人妻无码中文专区久久综合 | 在线A亚洲老鸭窝天堂 | 亚洲大香线伊人婷婷五月 | 精品人妻中文字幕有码在线 | 亚洲日本高清成人aⅴ片 | 日日插夜夜爽 | 久久爱黑人激情av | 沈樵精品国产成av片 | 东北露脸46熟妇ⅩⅩXX | 秋霞午夜av一区二区三区 | 日韩av有码在线 | 视频一区视频二区国产精品 | 扒开双腿吃奶呻吟做受 | 99福利资源久久福利资源 | 久久久久久国产精品免费无遮挡 | 在线无码VA中文字幕无码 | 在线观看a视频 | 日韩成人一级 | 把女的下面扒开添视频 | 亚洲激情四射视频中文字幕久久 | 成人免费在线网站 | 婷婷成人丁香五月综合激情 | 亚洲一二三四2021不卡 | 亚洲黄色第一页 | 日韩免费成人 | 欧美高清一区三区在线专区 | 日本少妇高潮喷水视频 | 丰满少妇xbxb毛片日本视频 | 亚洲国产无 |