97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
四虎影视在线免费观看,亚洲精品黄网站,欧美一级大黄大色毛片视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-IRGM/FITC Conjugated antibody (bs-4015R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4015R-FITC
英文名稱 Rabbit Anti-IRGM/FITC Conjugated antibody
中文名稱 FITC標記的免疫相關鳥苷三磷酸酶基因抗體
別    名 Irgm; IFI1; Iigp3; Immunity related GTPase family M protein 1; Immunity related GTPase family, M; Interferon inducible protein 1; IRGM1; LRG 47; LRG47; IRGM_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IRGM (62-105aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
IRGM belongs to a family of interferon-gamma inducible GTPases, belonging to the GTPase superfamily, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation. IRGM is primarily expressed in all cells derived from B-cell lineages, and is highly expressed in macrophages following IFN-gamma stimulation. IRGM has been shown to be required for host defences against a broad range of intracellular pathogens. Specifically, IRGM deficient mice show defects with intracellular microbial killing, phagosome maturation and autophagy. More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli.

Function:
Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity).

Subcellular Location:
Golgi apparatus membrane. Cell membrane. Cytoplasmic vesicle, phagosome membrane. Cytoplasmic vesicle, autophagosome membrane. Cell projection, phagocytic cup.

Tissue Specificity:
Widely expressed (at protein level). Expressed in several tissues including colon, small bowel and peripheral blood leukocytes.

DISEASE:
Defects in IRGM are the cause of susceptibility to inflammatory bowel disease type 19 (IBD19) [MIM:612278]. A chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.

Similarity:
Belongs to the interferon-inducible GTPase family.

Database links:
UniProtKB/Swiss-Prot: A1A4Y4.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

IRGM(又稱干擾素誘導蛋白1)屬于γ-干擾素誘導的GTP酶家族的一種,是一種復活基因,目前主要用于克羅恩氏?。ㄒ环N腸道的自身免疫性疾病)的研究。
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: av网站免费观看 | a天堂视频在线观看 | 美女精品 | 中文字幕无码肉感爆乳在线 | 国产亚洲一区二区三区四区 | 国产成人欧美一区二区三区一色天 | 日韩精品天堂 | ww939766com永久免费 | 5252色成人免费视频 | 99re6这里有精品热视频在线 | 亚洲国产AV天码精品果冻传媒 | 少妇宾馆把腿扒开让我添 | 久久一区二区三区精华液介绍 | 精品乱码久久久久久中文字幕 | 狠狠色狠狠色综合久久 | 人人鲁免费播放视频 | 国产粉嫩美女无套被中出 | 天堂а在线中文在线新版 | 中文字幕v亚洲ⅴv天堂 | 国产极品女主播国产区 | 国产精品久久久久77777 | 给我免费观看片在线观看 | 美利坚合众国毛片 | 亚洲综合无码日韩 | 在线看高清中文字幕一区 | 欧美大黄大色一级毛片 | 在线观看av网站永久 | aaa免费视频 | 偷窥国产亚洲免费视频 | 久久综合福利 | 国产精品国产三级国产普通话三级 | 91精品一区二区三区在线观看 | 国产三区视频 | 亚洲免费视频一区二区 | 91精品国产精品 | 91人人射 | 亚洲ΑV无码一区二区三区四区 | 让少妇爽到高潮视频 | 日日摸夜夜添夜夜添无码免费视频 | 久久天天躁狠狠躁夜夜婷 | 欧美成人看片一区二区三区尤物 |