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Rabbit Anti-G protein beta 4/BF488 Conjugated antibody (bs-3940R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3940R-BF488
英文名稱 Rabbit Anti-G protein beta 4/BF488 Conjugated antibody
中文名稱 BF488標記的G蛋白β4抗體/鳥嘌呤核苷酸結合蛋白β亞基4
別    名 G protein beta 4 subunit; GNB 4; GNB4; Guanine nucleotide binding protein (G protein) beta polypeptide 4; Guanine nucleotide binding protein beta 4 subunit; Guanine nucleotide binding protein beta polypeptide 4; Guanine nucleotide binding protein beta subunit 4; Guanine nucleotide binding protein subunit beta 4; Transducin beta chain 4; GBB4_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  轉錄調節因子  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G protein beta 4 (52-90aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Guanine nucleotide binding proteins (G proteins) are membrane associated, heterotrimeric proteins composed of three subunits: alpha, beta and gamma. The G protein beta subunit assumes a barrel shaped beta propeller structure containing WD40 repeats preceded by an N terminal alpha helix. The beta subunit forms a stable dimer with the gamma subunit. The alpha subunit only contacts the beta subunit in the dimer, lying on the opposite face from the gamma subunit. G proteins and their receptors (GPCRs) regulate systems as diverse as sensory perception, cell growth and hormonal regulation.

Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Subunit:
G proteins are composed of 3 units, alpha, beta and gamma.

Tissue Specificity:
Strongly expressed in lung and placenta, whereas it is weakly expressed in brain and heart.

Similarity:
Belongs to the WD repeat G protein beta family.
Contains 7 WD repeats.

Database links:

Entrez Gene: 59345 Human

Entrez Gene: 14696 Mouse

Entrez Gene: 294962 Rat

Omim: 610863 Human

SwissProt: Q9HAV0 Human

SwissProt: P29387 Mouse

SwissProt: Q3THF3 Mouse

SwissProt: Q3TY18 Mouse

SwissProt: Q3U2F9 Mouse

SwissProt: O35353 Rat

SwissProt: Q4V8I8 Rat

Unigene: 173030 Human

Unigene: 139192 Mouse

Unigene: 10844 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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