97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产精品无码素人福利免费 ,成人免费在线视频网站,最新日本中文字幕
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Glycogen/Gold Conjugated antibody (bs-2359R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-2359R-Gold
英文名稱 Rabbit Anti-Glycogen/Gold Conjugated antibody
中文名稱 膠體金標記的葡萄糖合成酶1抗體
別    名 Glycogen synthase 1 (muscle); Glycogen synthase 1; GSY; GYS; GYS1; EC 2.4.1.11; Glycogen synthase1; GYS 1; Starchsynthase muscle; UDP glucose glycogen glucosyltransferase; GYS1_HUMAN; Glycogen [starch] synthase, muscl.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  免疫學  信號轉導  生長因子和激素  轉錄調節因子  激酶和磷酸酶  糖尿病  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Glycogen synthase 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70% identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.

Function:
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

Subunit:
Interacts with GYG1.

Post-translational modifications:
Phosphorylation at Ser-8 by AMPK inactivates the enzyme activity. Primed phosphorylation at Ser-657 (site 5) by CSNK2A1 and CSNK2A2 is required for inhibitory phosphorylation at Ser-641 (site 3a), Ser-645 (site 3b), Ser-649 (site 3c) and Ser-653 (site 4) by GSK3A an GSK3B (By similarity). Phosphorylated at Ser-641 by PASK, leading to inactivation; phosphorylation by PASK is inhibited by glycogen. Dephosphorylation at Ser-641 and Ser-645 by PP1 activates the enzyme.

DISEASE:
Defects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; Metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.

Similarity:
Belongs to the glycosyltransferase 3 family.

Database links:

Entrez Gene: 2997 Human

Entrez Gene: 14936 Mouse

Entrez Gene: 690987 Rat

Omim: 138570 Human

SwissProt: P13807 Human

SwissProt: Q8VEB0 Mouse

SwissProt: Q9Z1E4 Mouse

SwissProt: A2RRU1 Rat

Unigene: 386225 Human

Unigene: 275654 Mouse

Unigene: 95278 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久人人九九 | 顶级少妇做爰视频在线观看 | 视频免费一区 | 亚洲精品永久在线观看 | 在线观看免费视频一区 | 成人毛片无码一区二区 | 好久不见在线观看免费高清 | 国产一级做a爰片久久 | 亚洲影院丰满少妇中文字幕无码 | 最近免费日本视频在线 | 日本japanese少妇漂亮 | 婷婷国产一区综合久久精品 | 日韩黄色大片在线观看 | 亚洲成人aa | 十八禁羞羞视频爽爽爽 | 亚洲乱码一二三四区 | 毛片久久一区二区三区网站 | 久久人人艹 | 中国一级黄色片子 | av在线免费观看网站 | 国产在线视频在线观看 | 久久久久久草 | VA在线看国产免费 | 永久免费精品影视网站播放器 | 性饥渴少妇AV无码毛片 | 黑人巨大精品欧美一区二区一 | 成人精品一区二区三区免费看 | 亚洲成AV人片在线观看橙子 | 欧美性xxxx狂欢老少配 | 久久不卡免费视频 | 手机av在线播放 | 国产精品粉嫩jk国产呦系列 | 婷婷九月综合 | 亚洲精品xx | 精品国产一区二区三区久久狼5月 | 国产精品日韩欧美一区二区 | 久久久999国产视频 成人综合久久综合 | 韩剧《上流社会》在线观看 | 在线观看特色大片免费视频 | 亚洲一区二区三区免费观看 | gogogo高清在线观看免费中国 |