97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
久久久久99啪啪免费,亚洲av成人网,xxxx在线视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Glycogen/Cy7 Conjugated antibody (bs-2359R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2359R-Cy7
英文名稱 Rabbit Anti-Glycogen/Cy7 Conjugated antibody
中文名稱 Cy7標記的葡萄糖合成酶1抗體
別    名 Glycogen synthase 1 (muscle); Glycogen synthase 1; GSY; GYS; GYS1; EC 2.4.1.11; Glycogen synthase1; GYS 1; Starchsynthase muscle; UDP glucose glycogen glucosyltransferase; GYS1_HUMAN; Glycogen [starch] synthase, muscl.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  生長因子和激素  轉錄調節因子  激酶和磷酸酶  糖尿病  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Glycogen synthase 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70% identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.

Function:
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

Subunit:
Interacts with GYG1.

Post-translational modifications:
Phosphorylation at Ser-8 by AMPK inactivates the enzyme activity. Primed phosphorylation at Ser-657 (site 5) by CSNK2A1 and CSNK2A2 is required for inhibitory phosphorylation at Ser-641 (site 3a), Ser-645 (site 3b), Ser-649 (site 3c) and Ser-653 (site 4) by GSK3A an GSK3B (By similarity). Phosphorylated at Ser-641 by PASK, leading to inactivation; phosphorylation by PASK is inhibited by glycogen. Dephosphorylation at Ser-641 and Ser-645 by PP1 activates the enzyme.

DISEASE:
Defects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; Metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.

Similarity:
Belongs to the glycosyltransferase 3 family.

Database links:

Entrez Gene: 2997 Human

Entrez Gene: 14936 Mouse

Entrez Gene: 690987 Rat

Omim: 138570 Human

SwissProt: P13807 Human

SwissProt: Q8VEB0 Mouse

SwissProt: Q9Z1E4 Mouse

SwissProt: A2RRU1 Rat

Unigene: 386225 Human

Unigene: 275654 Mouse

Unigene: 95278 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: av网址免费看 | 99久久精品免费观看国产 | av片播放 | 成人片免费看 | 亚洲中文成人中文字幕 | 91麻豆免费版 | 亚洲综合视频在线播放 | 99在线视频网站 | 日本黄色五级片 | 欧美精品中文字幕久久二区 | 久久久久久久福利 | 国产精亚洲视频 | 国产三级网 | 人妻无码中文专区久久综合 | av在线天堂亚洲 | 00271最新网站地址一 | 欧美性猛交xxxx乱大交退制版 | 亚洲一区二区三区免费在线观看 | 婷婷日日| 日日碰狠狠丁香久燥 | 91久久国产综合久久91精品网站 | 337P大尺度啪啪人体 | 在线观看中文字幕一区 | 欧美在线欧美在线 | 国产一区色 | 最新日韩AV网址在线观看 | 亚洲黄色在线免费观看 | 92精品国产自产在线观看481页 | 91av色| 午夜精品成人一区二区 | 蜜桃臀AV高潮无码 | 免费播放av | 国产成人免费一区二区三区 | 超碰网站在线 | 国产激情视频一区二区 | 色妞www精品视频观看软件 | 国产精品99久久久久久小说 | 日韩处女网站 | 九一免费在线观看 | 伊人久久狼人 | 午夜羞羞影院免费播放在线观看 |