97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
丰满多毛少妇做爰视频,网站黄色在线观看,91快看
Rabbit Anti-GDNF/BF350 Conjugated antibody (bs-1024R-BF350)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1024R-BF350
英文名稱 Rabbit Anti-GDNF/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的膠質(zhì)細(xì)胞源性神經(jīng)營(yíng)養(yǎng)因子抗體
別    名 glial cell line derived neurotrophic factor; Astrocyte derived trophic factor 1; Astrocyte derived trophic factor; ATF 1; ATF 2; ATF1; ATF2; Glial cell derived neurotrophic factor; Glial derived neurotrophic factor; HFB1 GDNF; GDNF_HUMAN; Atf; gdnf; Glial Cell Line Derived Neurotrophic Factor; Glial cell line-derived neurotrophic factor; Glial derived neurotrophic factor; hGDNF; HSCR3.   
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  細(xì)胞凋亡  生長(zhǎng)因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 15kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GDNF
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Neurobiology. Neurotrophins. Neuroscience.
This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease.


Function:
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted.

Tissue Specificity:
In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.

DISEASE:
Defects in GDNF may be a cause of Hirschsprung disease type 3 (HSCR3) [MIM:613711]. In association with mutations of RET gene, defects in GDNF may be involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
Defects in GDNF are a cause of congenital central hypoventilation syndrome (CCHS) [MIM:209880]; also known as congenital failure of autonomic control or Ondine curse. CCHS is a rare disorder characterized by abnormal control of respiration in the absence of neuromuscular or lung disease, or an identifiable brain stem lesion. A deficiency in autonomic control of respiration results in inadequate or negligible ventilatory and arousal responses to hypercapnia and hypoxemia.

Similarity:
Belongs to the TGF-beta family. GDNF subfamily.

Database links:

Entrez Gene: 2668 Human

Entrez Gene: 14573 Mouse

Entrez Gene: 25453 Rat

Omim: 600837 Human

SwissProt: P39905 Human

SwissProt: P48540 Mouse

SwissProt: Q07731 Rat

Unigene: 248114 Human

Unigene: 4679 Mouse

Unigene: 53970 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

神經(jīng)生物學(xué)相關(guān)蛋白
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 阿娇艳z门照片无码av4i | 色吧网站 | 992tv精品视频tv在线观看 | 天天色宗合 | 国产真实夫妇对白视频 | 免费观看黄色av | 久久久久久久久18久久久 | 国产女合集小岁9三部 | 国产午夜日韩不卡一区 | 久操福利视频 | 日日干夜夜爽 | 宅男66LU国产在线观看 | 国内视频精品 | 99re在线视频精品 | 久久精品无码专区免费东京热 | 51精品国产人成在线观看 | 1024在线观看国产天堂 | 无码少妇高潮喷水A片免费 欧美性xxxx视频 | 久久一二区 | 在线观看国产一区二区三区 | 亚洲综合在线另类色区奇米 | 久色88| 国产精品久久久久久免费一级 | www.黄色网址.com | 久久精品美女 | 日本一区二区免费在线播放 | 日韩精品一区二区三区国语自制 | 国产四区| 国产精品久久久久久久久免费樱桃 | 精品国产一区二区三区麻豆小说 | 亚洲一级视频在线观看 | 91国产一区 | 亚洲黄色在线免费观看 | 不卡在线一区2区三区 | 香蕉97超级碰碰碰视频 | 午夜一级黄色大片 | 尤物丰满少妇大尺度喷血写真 | 日韩精品一区二区三区免费观看 | 国产精品一区一区三区 | 99影音| 日韩大片在线观看 |