97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲你懂的,久久影院免费,黄色网页视频在线观看
Rabbit Anti-TFDP2/RBITC Conjugated antibody (bs-7660R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-7660R-RBITC
英文名稱 Rabbit Anti-TFDP2/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的轉(zhuǎn)錄因子E2F二聚體蛋白2抗體
別    名 DP2; E2F dimerization partner 2; Tfdp2; TFDP2_HUMAN; Transcription factor Dp 2; Transcription factor Dp-2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49 kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TFDP2/DP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis. Tissue specificity: High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.

Function:
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis.

Subunit:
Component of the DRTF1/E2F transcription factor complex. Forms heterodimers with E2F family members. The complex can interact with hypophosphorylated retinoblastoma protein RB1 and related proteins (RBL1 and RBL2) that inhibit the E2F transactivation domain. During the cell cycle, RB becomes phosphorylated in mid-to-late G1 phase, detaches from the DRTF1/E2F complex rendering E2F transcriptionally active. Viral oncoproteins, notably E1A, T-antigen and HPV E7, are capable of sequestering RB protein, thus releasing the active complex. Interacts with GMCL (By similarity). Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.

Subcellular Location:
Nucleus.

Tissue Specificity:
High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.

Post-translational modifications:
Ser-24 is probably phosphorylated by CDK2.

Similarity:
Belongs to the E2F/DP family.

Database links:

Entrez Gene: 7029 Human

Entrez Gene: 300947 Rat

Omim: 602160 Human

SwissProt: Q14188 Human

Unigene: 379018 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 在线毛片免费 | 亚州av久久精品美女模特图片 | 亚洲成av人不卡无码影片 | 亚洲综合色婷婷六月丁香宅男大增 | 亚洲AV综合色区无码二区偷拍 | 51成人 | 暗夜在线观看 | 国产精品久久久久久婷婷动漫 | 137肉体写真日本裸交 | 91久久精品国产免费一区 | 日韩在线精品视频 | 蜜桃传免费看片www 蜜臀av免费一区二区三区水牛 | 免费超级淫片日本高清视频 | 久久久久久国产精品无码超碰 | 美女大量吞精在线观看456 | 男人影音 | 亚洲国产日韩av | 天天看天天摸天天操 | 亚洲丁香婷婷久久一区二区 | YW尤物AV无码国产在线观看 | 无码国内精品人妻少妇蜜桃视频 | 偷窥国产亚洲免费视频 | 美女大胆作爱全过程 | 91精品国产综合久久小仙女图片 | 亚洲hh | 十八禁无码免费网站 | 亚洲成av人在线看 | 色爱综合网中文字幕第1页 国产农村妇女毛片精品久久 | 无码AV波多野结衣久久 | 欧美性受xxxx黑人xyx | 亚洲中文久久精品81 | 日本不卡免费在线观看 | Chinese国产HD精品实拍 | 操操操操网 | 亚洲AV久久久噜噜噜熟女软件 | 国产又大又硬又粗 | 人人超碰人人爱超碰国产 | 三个男人躁我一个爽公交车上 | 日本大片在线免费观看 | 免费国产视频 | 亚洲欧洲偷自拍图片区 |