97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日本黄漫在线观看,精品免费一区二区三区,91大神在线观看精品一区
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-ERCC6L/Biotin Conjugated antibody (bs-6380R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6380R-Bio
英文名稱 Rabbit Anti-ERCC6L/Biotin Conjugated antibody
中文名稱 生物素標記的發育相關蛋白ERCC6L/乙醇致畸因子抗體
別    名 ATP dependent helicase ERCC6 like; DNA excision repair protein ERCC 6 like; ERCC 6L; ERCC6L; Excision repair cross complementing rodent repair deficiency complementation group 6 like; Excision repair protein ERCC6 like; FLJ20105; MGC131695; PICH; Plk1 interacting checkpoint helicase; SNF2/RAD54 family protein; Tumor antigen BJ HCC 15; ERC6L_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發育生物學  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 141kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ERCC6L
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.

Function:
DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

Subunit:
Interacts with PLK1, which phosphorylates it. Both proteins are mutually dependent on each other for correct subcellular localization.

Subcellular Location:
Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores, inner centromeres and thin threads connecting separating chromosomes even during anaphase. In prometaphase cells, it mostly concentrates in between kinetochores. In metaphase, it localizes to numerous thin threads that stretch between sister kinetochores of the aligned chromosomes and are composed of catenated centromeric DNA. Evolution from inner centromeres to thin threads takes place in response to tension. Resolution of thin threads requires topoisomerase 2-alpha (TOP2A) after anaphase onset.

Post-translational modifications:
Phosphorylation by PLK1 prevents the association with chromosome arms and restricts its localization to the kinetochore-centromere region.

Similarity:
Belongs to the SNF2/RAD54 helicase family.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Contains 2 TPR repeats.

Database links:

Entrez Gene: 54821 Human

Omim: 300687 Human

SwissProt: Q2NKX8 Human

Unigene: 47558 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 99热6这里只有精品 国产一区=区 | 国产精品久久久亚洲一区 | 丰满妇女做A级毛片 | 337P亚洲日本中国大胆69 | 二区三区偷拍浴室洗澡视频 | 18禁强伦姧人妻又大又粗 | 亚洲欧美日韩中文高清WWW777 | 亚洲ΑV无码一区二区三区四区 | 男人日女人逼的视频 | 暗夜在线观看 | 亚洲有吗在线观看 | 91精品国产综合久久久久久首页 | 三区在线观看 | 中文字幕免费在线视频 | 成年人免费观看网站 | av一区在线观看 | 免费jlzzjlzz在线播放 | 最新大地资源网在线观看免费 | 亚洲最新在线视频 | 无码专区无码专区视频网址 | 老子午夜精品888无码不卡 | 追你而来免费观看 | 97色在线视频 | 日韩在线看片免费人成视频播放 | 国产h在线观看 | 精品久久国产精品 | 精品亚洲一区二区三区在线观看 | 精品成人一区二区三区四区 | 一区两区三区四区乱码国产精品 | www国产成人免费观看视频深夜成人网 | 吃奶呻吟打开双腿做受视频 | 亚洲老司机在线 | 色哟哟最新在线观看入口 | 99视频免费 | 2级黄色片| 在线免费看av的网站 | 在线免费观看视频黄 | 久久精品人妻无码一区二区三区 | 亚洲欧美中文日韩av一区 | 国产视频九九 | 久久字幕精品一区 |