97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
成年在线网69站,亚洲午夜高清国产拍,国产被窝福利一区二区
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-ERCC6L/RBITC Conjugated antibody (bs-6380R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6380R-RBITC
英文名稱 Rabbit Anti-ERCC6L/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的發育相關蛋白ERCC6L/乙醇致畸因子抗體
別    名 ATP dependent helicase ERCC6 like; DNA excision repair protein ERCC 6 like; ERCC 6L; ERCC6L; Excision repair cross complementing rodent repair deficiency complementation group 6 like; Excision repair protein ERCC6 like; FLJ20105; MGC131695; PICH; Plk1 interacting checkpoint helicase; SNF2/RAD54 family protein; Tumor antigen BJ HCC 15; ERC6L_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發育生物學  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 141kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ERCC6L
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.

Function:
DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

Subunit:
Interacts with PLK1, which phosphorylates it. Both proteins are mutually dependent on each other for correct subcellular localization.

Subcellular Location:
Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores, inner centromeres and thin threads connecting separating chromosomes even during anaphase. In prometaphase cells, it mostly concentrates in between kinetochores. In metaphase, it localizes to numerous thin threads that stretch between sister kinetochores of the aligned chromosomes and are composed of catenated centromeric DNA. Evolution from inner centromeres to thin threads takes place in response to tension. Resolution of thin threads requires topoisomerase 2-alpha (TOP2A) after anaphase onset.

Post-translational modifications:
Phosphorylation by PLK1 prevents the association with chromosome arms and restricts its localization to the kinetochore-centromere region.

Similarity:
Belongs to the SNF2/RAD54 helicase family.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Contains 2 TPR repeats.

Database links:

Entrez Gene: 54821 Human

Omim: 300687 Human

SwissProt: Q2NKX8 Human

Unigene: 47558 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 午夜香吻高清观看视频在线 | 大地资源二在线观看官网 | 国产精品自在在线免费 | 大香伊蕉最新视频 | 亚洲精品无码一区二区三区污 | 无码精品人妻一区二区三区老牛 | 精品人妻少妇一区二区三区 | 成人激情视频网站 | 精品少妇爆乳无码av无码专区 | 亚洲精品久久久久久中文传媒 | 中文无码一区二区视频在线播放 | 北条麻妃中文字幕 | 欧美黑人XXXX又粗又长 | 亚洲精品永久在线观看 | 精品欧美不卡一区二区在线观看 | 国产av一二三 | 国产手机在线αⅴ片无码观看 | www.黄色网址.com | 国产永久视频 | 久久亚洲sm情趣捆绑调教 | 国产精品三级 | 午夜在线观看影院 | 久久免费视频国产 | 日本黄色录像视频 | 亚洲免费视频播放 | 超碰网站在线 | 久久久久久久久久久久久久久国产 | 亚洲黄色特级片 | 狠狠狠的在啪线香蕉亚洲应用 | 免费黄在线看 | 无码H肉3D动漫在线观看 | 国产农村妇女一区二区三区 | 国产成人a在线视频免 | 久草影视在线 | 欧美亚洲日韩国产网站 | 亚州av在线播放 | 亚洲精品成人福利网站 | 免费成人午夜视频 | 国产成人无码a区精油按摩 大地资源在线观看免费高清官网 | 亚洲日韩av无码一区二区三区人 | 中文字幕永久在线播放 |